Director, Project Portfolio Management PMO

Introduction to role:

Are you ready to steer a high-impact infrastructure capital project portfolio that enables our science strengthens our manufacturing and ultimately helps deliver medicines to patients faster and more safely Do you thrive at the intersection of strategy execution and cross-functional leadership turning complex portfolios into transparent data-driven decisions

As Director Project Portfolio Management you will lead the site Operations PMO and shape how capital and infrastructure investments are prioritized and delivered across both GMP and non-GMP environments. Your leadership will connect project outcomes to business goals balancing quality safety speed and sustainability. You will bring discipline and clarity to a dynamic environment establishing governance elevating standards and empowering teams to perform at their best.

This is a role for a bold practical leader who can set direction coach teams and make tough choices with confidence. You will champion a culture of continuous improvement using digital tools and transparent metrics to reduce risk improve predictability and unlock capacity for our long-term site strategy.

Accountabilities:

• PMO Leadership and Strategy: Provide strategic leadership and direction to the Site Operations PMO overseeing all capital and infrastructure projects across GMP and non-GMP portfolios to deliver against site and enterprise objectives.

• Governance and Standards: Develop implement and maintain PMO governance frameworks project management standards and reporting tools that drive consistency quality and compliance across the portfolio.

• People Leadership: Lead a team of Project Managers and Project Engineers set clear performance expectations manage workload and support professional development to build a high-performing PMO.

• Portfolio Prioritization and Resource Planning: Oversee portfolio prioritization resource planning and execution to ensure projects align with business objectives and capital investment strategy maximizing value and minimizing disruption.

• Financial Stewardship: Partner with Finance to manage multi-year capital budgets forecasts and expenditure tracking ensuring accurate visibility and alignment with long-term site investment planning.

• Performance Transparency: Establish and maintain portfolio-level dashboards KPIs and reports that provide clear timely transparency to senior leadership and enable data-informed decision-making.

• Risk Change and Issue Management: Drive rigorous risk management change control and issue resolution across the portfolio ensuring timely mitigation and escalation to protect schedule cost and quality.

• Cross-Functional Compliance: Collaborate with Engineering Quality SHE and Procurement to ensure projects meet technical safety and regulatory requirements from design through handover.

• Audit and Inspection Readiness: Ensure readiness for audits and inspections through robust documentation quality control and adherence to governance.

• Innovation and Continuous Improvement: Champion innovation and continuous improvement across the PMO by leveraging digital tools benchmarking and lessons learned to enhance predictability and performance.

• Culture and Ways of Working: Foster a culture of collaboration accountability and operational excellence across all functions involved in project delivery modeling behaviors that elevate quality and safety alongside speed.

• GMP Portfolio Oversight: Oversee the GMP project portfolio supporting manufacturing QC and analytical spaces ensuring full regulatory compliance and audit readiness; collaborate with Quality and Validation to maintain a state of control; ensure technical governance for GMP utilities controlled environments and validated systems.

• Non-GMP Portfolio Oversight: Oversee the non-GMP project portfolio including research vivarium and office environments; partner with Workplace Services and Lab Ops to enable long-term site strategy and capacity growth; implement sustainability and energy efficiency standards within project delivery to support Ambition Zero Carbon objectives.

Essential Skills/Experience:

• Proven ability to provide strategic leadership and direction to a PMO overseeing capital and infrastructure projects across GMP and non-GMP portfolios.

• Demonstrated experience developing implementing and maintaining PMO governance frameworks project management standards and reporting tools.

• Track record of leading teams of Project Managers and Project Engineers setting performance expectations managing workload and supporting professional development.

• Experience overseeing portfolio prioritization resource planning and execution to align projects with business objectives and capital investment strategy.

• Partnership with Finance to manage multi-year capital budgets forecasts and expenditure tracking aligned with long-term site investment planning.

• Experience establishing and maintaining portfolio-level dashboards KPIs and reports to provide transparency to senior leadership and drive data-informed decision-making.

• Strong capability in driving risk management change control and issue resolution across a project portfolio with timely mitigation and escalation.

• Collaboration with Engineering Quality SHE and Procurement to ensure projects meet technical safety and regulatory requirements.

• Ensuring readiness for audits and inspections through robust documentation quality control and adherence to governance.

• Championing innovation and continuous improvement across the PMO by leveraging digital tools benchmarking and lessons learned.

• Fostering a culture of collaboration accountability and operational excellence across project delivery functions.

• Oversight of GMP project portfolios supporting manufacturing QC and analytical spaces including maintaining a state of control with Quality and Validation teams and technical governance for GMP utilities controlled environments and validated systems.

• Oversight of non-GMP project portfolios including research vivarium and office environments; partnering with Workplace Services and Lab Ops to enable long-term site strategy and capacity growth; implementing sustainability and energy efficiency standards within project delivery to support Ambition Zero Carbon objectives.

Desirable Skills/Experience:

• Experience scaling PMO capabilities in fast-moving complex site environments.

• Proven ability to embed Lean principles into project delivery to elevate quality and safety as well as speed.

• Proficiency with digital portfolio management toolsets and analytics enabling real-time visibility and predictive insights.

• Track record delivering capital projects across both GMP manufacturing and R&D facilities balancing diverse stakeholder needs.

• Familiarity with vivarium standards and laboratory planning best practices.

• Strong stakeholder engagement and data storytelling skills to influence senior leaders and secure alignment.

• Professional certifications such as PMP or equivalent and experience with stage-gate governance models.

When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. We work five days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

The annual base pay (or hourly rate of compensation) for this position ranges from $141751 to $ positions offer eligibility for various incentivesan opportunity to receive short-term incentive bonuses equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs paid time off (i.e. vacation holiday and leaves) as well as health dental and vision coverage in accordance with the terms of the applicable plans.

Why AstraZeneca:

Here your portfolio leadership directly accelerates the delivery of medicines to patients while shaping how our sites evolve for the future. We bring diverse experts together to solve hard problems quickly pairing disciplined governance with an enterprising Lean mindset that raises quality and safety as we increase speed. You will influence decisions that matterfrom capital strategy and audit readiness to energy-efficient design that advances our Ambition Zero Carbon commitmentsbacked by teams who value kindness alongside ambition and by leaders who trust you to lead meaningful change.

Call to Action:

Step in to lead a mission-critical portfolio and create lasting impacttake the next step today to shape how our sites deliver for science for teams and for patients.

Date Posted

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.