Senior MES Engineer – Life Sciences Manufacturing Execution Systems

Senior MES Engineer Life Sciences Raleigh NC Hybrid

Location: Raleigh NC (Hybrid) 25% Travel Required
Salary: $145K$180K Base 2035% Bonus
Schedule: Full-Time Hybrid

About Us:
We are a 100% employee-owned ENR Top 500 engineering firm with 40 years of experience delivering complex automation MES and system integration solutions. With offices across the U.S. and over 500 experts on staff we provide life sciences and industrial clients with innovative compliant and efficient manufacturing solutions.

Role Overview:
We are seeking a Senior MES Engineer to lead the design implementation and commissioning of MES (Manufacturing Execution System) solutions in the Life Sciences industry. This is a leadership role for a technically skilled hands-on professional capable of architecting MES systems guiding teams and driving client success. You will also have the opportunity to develop and lead our Raleigh MES office.

Key Responsibilities:

• Lead MES solution projects from concept to commissioning ensuring compliance with cGMP and 21 CFR Part 11.
• Act as Solution Architect for MES integrations across ERP LIMS control systems (PLC/DCS) historians and reporting platforms.
• Deploy MES platforms such as Werum PAS-X Sepasoft or POMS for Life Sciences manufacturing.
• Develop project plans budgets and schedules and oversee project profitability up to $1M.
• Mentor and lead engineering teams guiding junior engineers and technicians.
• Collaborate directly with clients to gather requirements recommend optimal system designs and deliver efficient compliant solutions.
• Support business development efforts including trade shows associations and client relationship growth.

Qualifications:

• Bachelor of Science in Engineering Computer Science or Applied Sciences required.
• 10 years MES experience with at least 4 years in Life Sciences.
• Proven experience with MES deployment integration and full lifecycle management (concept design implementation testing commissioning).
• Deep knowledge of GAMP5 S88 and S95 standards for EBR and process integration.
• Familiarity with ERP LIMS DeltaV SAP PI Maximo and relational databases (SQL Oracle).
• Strong understanding of manufacturing processes warehouse/inventory management in GMP environments.
• Ability to travel up to 25%.
• Excellent leadership problem-solving and communication skills.

Why Join Us:

• Be part of a 100% employee-owned ESOP company with career growth potential.
• Lead innovative Life Sciences MES projects with autonomy and impact.
• Hybrid work model with access to the Raleigh office and client sites.
• Competitive base salary plus discretionary bonus (2035%).
• Join a top-rated system integrator and ENR Top 500 firm with a long-standing industry reputation.