The Psychiatric Biomarkers Network (PBN) ( is a consortium of academic and industry partners seeking to discover fluid molecular biomarkers for schizophrenia and bipolar disorder to enable more efficient and effective drug development for these pharmacologically underserved mental illnesses. The consortium is recruiting and longitudinally following patients and unaffected control subjects collecting blood and cerebrospinal fluid samples and phenotyping participants with a battery of clinical and cognitive measures. Our goal is to enable the stratification of this mechanistically and clinically heterogeneous patient population into subgroups based on their underlying biology in order to better match patients with the right treatments both in clinical trials and ultimately in clinical practice.
The PBN is led by the Stanley Center for Psychiatric Research at Broad. We are seeking a motivated and enthusiastic biostatistician or computational biologist to apply sophisticated statistical methods and models to the growing body of PBN data and to other relevant datasets from biobanks and consortia partners to drive hypothesis generation and novel insights. Based on proteomics targeted molecular assay data and extensive clinical and cognitive phenotype data we seek to identify proteins that define subgroups of patients correlate with symptoms or cognition and track or predict disease progression over time.
QUALIFICATIONS
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IC
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