Intern- Bioinformatics

AskBio Inc. a wholly owned and independently operated subsidiary of Bayer AG is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular central nervous system cardiovascular and metabolic disease indications with a clinical-stage pipeline that includes investigational therapeutics for congestive heart failure limb-girdle muscular dystrophy multiple system atrophy Parkinsons disease and Pompe disease. AskBios gene therapy platform includes Pro10 an industry-leading proprietary cell line manufacturing process and an extensive array of capsids and promoters. With global headquarters in Research Triangle Park North Carolina and European headquarters in Edinburgh Scotland the company has generated hundreds of proprietary capsids and promoters several of which have entered pre-clinical and clinical testing.

Our vision: Pioneering science to create transformative molecular medicines.

Our mission: Lead innovative science and drive clinical outcomes to transform peoples lives.

Our principles:

• Advance innovative science by pushing boundaries.

• Bring transformative therapeutics to patients in need.

• Provide an environment for employees to reach their fullest potential.

Our values:

• Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.

• Cultivate Collaboration. Strive to be the best teammate actively listen openly communicate and embrace diverse points of view.

• Embrace Responsibility. We are humbled by the enormity of our hold a relentless commitment to advance science and clinical outcomes for our patients families and caregivers.

• Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.

• Act with Uncompromising Integrity. Be honest transparent and committed to doing whats right in every situation. Make clear commitments and follow through.

Position Summary

This internship provides an opportunity for a highly motivated doctoral student to gain hands-on experience applying bioinformatics and machine learning approaches to real biological data within a gene therapy research environment.

The intern will join the Bioinformatics and AI/Machine Learning team at AskBio and contribute to a defined project focused on the integration and analysis of AAV capsid production and sequence-based data within AskBios proprietary bioinformatics platform PromPT. The project will emphasise data curation exploratory analysis and the application of existing machine learning models.

Working closely with experienced bioinformaticians data scientists and experimental scientists the intern will learn how computational analyses are designed implemented validated and interpreted in a translational research setting. The internship includes structured mentoring regular feedback and exposure to best-practice software and data workflows.

At the end of the internship the intern will deliver a final presentation describing the project the analyses performed and key learnings.

The intern will report to the Senior Director Bioinformatics and AI/Machine Learning and will be based on-site in the Edinburgh office.

Job Responsibilities

• Assist in identifying collecting and curating AAV capsid production and sequence-related datasets from internal and public sources.

• Perform data cleaning quality control and exploratory data analysis

• Support the application and evaluation of existing machine learning or statistical models related to AAV production or sequence features.

• Assist with the integration of data outputs and model results into PromPT for downstream analysis and visualisation.

• Develop clear visualisations and summary analyses to support biological interpretation of results.

• Collaborate with bioinformaticians ML scientists and experimental researchers to understand project context and user needs.

• Participate in documentation code reviews and version-controlled development workflows.

• Assist with testing and validation of analysis outputs.

• Communicate progress through regular discussions and updates with the project team.

• Prepare and deliver a final presentation summarising the project methods results and learning outcomes.

Minimum Requirements

• Must be pursuing a Doctorate degree in Informatics Bioinformatics Data or Computer Science AI or Machine Learning or a related field

• Must have completed their first year at the time of application

• Coursework or academic experience in one or more of the following: bioinformatics machine learning data science or computational biology

• Basic programming experience in Python or a similar scientific programming language

• Familiarity with fundamental concepts in machine learning or statistical data analysis

• Interest in applying computational methods to biological or genomic data

• Strong analytical and problem-solving skills

• Ability to communicate technical ideas clearly to both technical and non-technical audiences

• Organised curious and eager to learn in a collaborative research environment

• Available to work full-time on-site in the Edinburgh office during the summer internship period

Preferred Education Experience and Skills

• Prior research internship or project experience in bioinformatics machine learning or data science

• Exposure to biological sequence data (e.g. DNA RNA or genomic datasets)

• Familiarity with Linux or command-line environments

• Experience with data visualisation libraries or tools

• Awareness of software development best practices such as version control (e.g. Git)

• Interest in gene therapy genomics or computational biology research

AskBio Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race color religion gender sexual orientation gender identity national origin age disability veteran status or any other protected status prohibited under Federal State or local laws. All employment decisions are based on valid jobrelated requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website you may request a reasonable accommodation to express interest in a specific opening by calling us at or sending us an email at .

Agencies: Please do not contact any employee at AskBio about this requisition. Any resume submitted by a recruitment agency to any employee at AskBio through any medium will be deemed the sole property of AskBio unless the agency was engaged by AskBio Talent Acquisition team to recruit for that position. All agencies must have a prior executed service agreement with AskBio prior to any search engagement. If a candidate who was submitted outside of the AskBio agency process is hired by AskBio no fee or payment of any kind will be paid to the agency.