Scientist I, Cell Culture Process Development

We are seeking an enthusiastic and creative hands-on scientist to join the Cell Culture Process Development group within PDS&T Biologics at AbbVie Bioresearch Center in Worcester MA. As part of the Cell Culture Development organization you will support process development and technology transfer activities for cell culture processes contributing to the clinical manufacturing and commercialization of therapeutic proteins in the AbbVie pipeline. Additionally the team provides subject matter expertise and experimental support for the production of commercial biologics. The ideal candidate will work effectively both independently and collaboratively within a dynamic team environment.

Key Responsibilities:

• Develop and characterize highly-productive CHO cell culture processes suitable for cGMP biotherapeutic manufacturing within project timelines performing technical transfer and manufacturing support activities.
• Conceive and execute scientific research and development to significantly improve platform processes and workflows develop new methods build technical expertise and deepen scientific understanding.
• Design execute and analyze cell culture experiments using Design of Experiments (DOE) principles and report data summary packages for multi-variate analysis.
• Work collaboratively and cross-functionally with colleagues in other functional areas (Analytical Development Cell Line Development Discovery Manufacturing and Quality).
• Effectively communicate scientific data and concepts to internal and external audiences through reports presentations and manuscripts.
• Author and review technical reports protocols and other key documents.
• Understand and adhere to corporate standards regarding code of conduct safety documentation and GMP compliance.

Preferred Qualifications:

• M.S. in biology biochemical/chemical engineering or life sciences related disciplines with 2 years of industrial experience; or B.S. in biochemical/chemical engineering or life sciences related disciplines with 5 years of industrial experience.
• Hands-on experience with upstream mammalian suspension cell culture using bench scale bioreactors deep well plates and shake flasks.
• Understanding of cell culture processes (e.g. cell culture process development process scale up and scale down recombinant protein production protein characterization).
• Experience with statistical data analysis tools such as design of experiment multivariate data analysis and modeling.
• Experience with automated liquid handling systems and high throughput culture is a plus
• Excellent interpersonal and communication skills. Strong scientific curiosity with a passion for problem-solving and optimization. Self-motivated with excellent attention to detail and ability to multi-task. Strong organizational planning and trouble-shooting skills.

Qualifications :

• Bachelors Degree or equivalent education with typically 5 years of experience or Masters Degree or equivalent education with typically two years of experience.
• Theoretical and practical knowledge to carry out the job functions.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.

• We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.

• This job is eligible to participate in our short-term incentive programs. 

Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. 

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Work :

No

Employment Type :

Full-time