The Meydan Lab is interested in the mechanisms of protein synthesis and the role of translation regulation and ribosomes in human health. We use various biochemistry techniques sequencing of ribosome protected mRNA fragments (a.k.a ribosome profiling (Ribo-seq) disome profiling (Disome-seq) and mitoribosome profiling) and RNA-seq in model systems of Saccharomyces cerevisiae(budding yeast) immortalized human cells and neurons differentiated from induced pluripotent stem cells (iPSCs) to address our questions.
AssistsinResearchandDevelopment:
Collects data using appropriate lab experiments procedures and techniques
Maintains knowledge of current literature on Meydan Labs research focus
Preparesbuffersandreagents
Generates and maintains plasmids yeast strains andmammalian cell lines
Analyzes and interprets data with assistance of other members of the laboratory
Writesandupdateslaboratoryprotocols
Reports on the status of research activities in oral and written formats
Assemblesandcompilesresearchdataforpresentationsand/orpublications
Maintenance
Conducts generallabmaintenance
Assists in set up operation and maintenance oflaboratoryequipment includingbutnotlimitedto biosafety cabinets incubatorscentrifuges etc.
Performsadministrativeduties
Monitors inventory of supplies and assists with ordering
Participatesinone-on-onemeetings and group lab meetingstodiscussprojectprogress
Othertasksasdirectedbysupervisor
Thispositiondoesnothavesupervisoryresponsibility.
Thepositionreportsadministrativelyand functionallytothePI.
ABachelorsdegreein biochemistrybiological scienceschemistryor relatedfield fromanaccreditedinstitutionofhighereducationisnecessary.
Knowledge and experience with mammalian cell culture iPSC and neurons is preferred.
Knowledge and experience with plasmid cloning is preferred.
Knowledge and experience with next generation sequencing is preferred.
Knowledge and experience of yeast growth and maintenance techniques is preferred.
Experience with organization inventory and record keeping is preferred.
Excellent organizational and communications skills (both verbal and written) are preferred.
Required Experience:
Junior IC
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