Global Market Development Lead, Mevrometostat

At Pfizer Oncology we are committed to Outdo Cancer by advancing transformative medicines wherever we can make a profound difference in the lives of patients. Pfizer Oncology is focused on extending its leadership in genitourinary cancers and we are committed to developing and delivering a broad portfolio of medicines in prostate cancer that define standards of care for patients across the treatment continuum. Mevrometostat is a first-in-class small-molecule EZH2 inhibitor in Phase-3 development for the treatment of advanced prostate cancer (aPC). There are currently 3 on going Phase 3 trials with readouts expected in& 2028. When used in combination with androgen receptor pathway inhibitors (ARPIs; like XTANDI) Mevrometostat may overcome ARPI resistance- a common cause of PC disease progression. Prostate cancer is the 2nd most common cancer in men worldwide and the 5th most common cause of cancer death among men mCRPC represents an addressable patient population of 52000 patients in the addition to the Phase 3 trials we continue to evaluate further development opportunities for Mevrometostat in earlier lines of prostate cancer.

ROLE SUMMARY

As a first in its class EZ-H2 inhibitor in prostate cancer Mevrometostat is well positioned to drive the narrative and value of EZH2 inhibition in PC . The Market Development Lead will be responsible for designing and launching a robust commercial market development plan that will enable Pfizer to define this new class of treatment & establish EZH2 as viable target in metastatic prostate cancer. Historically HCPs have been slow to adopt new SoC therapies in PC therefore success will be rooted in overcoming strong adoption hesitancy and putting forth a clear and compelling understanding of EZH2 and its differentiation proposition from other treatment options both within class and across classes. These activities when done successfully can significantly impact the commercial success of mevrometostat by generating excitement about this new target therefore optimizing the EZH2i initial uptake and peak class share.

Mevrometostats arrival will also become a powerful opportunity to illuminate and position Pfizer as a commanding leader in Prostate Cancer. Building on an already a strong existing portfolio of products (Xtandi Orgoyvx (US Only) Talzena Globally) and now with Mevrometostat s arrival this becomes a marquee opportunity to bolster Pfizers already strong heritage. Leveraging a clear co-positioning strategy as the roadmap the market development lead will be critical partner in developing the portfolio leadership approach in order to clearly express the depth and breadth of the many unmet needs our products support in Prostate Cancer. These efforts not only strengthen reasons to believe in our prostate portfolio but will buoy the credibility and reasons to believe in our new launch as well.

Our market development efforts are critical and therefore the selected candidate will need to understand not only the launch excellence process but also be attuned to identifying and understanding key mPC market dynamics in order to hone in on deep & robust insights that will drive needed behavior changes. The candidate should have a proven track record of working in a matrix team environment with multiple regional marketing and cross-functional partners.

ROLE RESPONSIBILITIES

• Lead our pre-launch strategic market development efforts to both strengthen understanding and awareness of thisvery new and innovative MOA (the key role EZH2 plays in prostate cancer) to all critical key stakeholders and target audiences

• Build and execute a compelling unbranded campaign and a strong market development tactical plan to support this effort

• Design and map a robust market development promotional plan from omnichannel to medical education to congress engagement and define investment priority

• Ensure coordination of the market development strategy at the global regional and local levels and ensure consistency of approach and implementation

• Determine the longer term strategy evolutionary needs of our market development efforts as the brand approaches earlier line indications (2028) for an mCSPC indication.

• Set market development engagement priorities by stakeholder (HCP/Oncology/Urology/Nurses/Payers and Patients)

• Partner across the portfolio asset teams to identify approaches for optimally expressing Pfizer Leadership Narrative in Prostate Cancer

• Leverage our co-positioning strategy efforts as a springboard to identify and articulate Pfizers support for HCPs/Patients across the mPC continuum

• Ensure our PC leadership arc narrative and messages are aligned to work within the umbrella of a broader Pfizer Oncology leadership platform

• Champion & synthesize customer insights and translate key critical insights into Global strategy and action plans

• Define market development success metrics and KPIs for tracking impact and progress

• Manage CoLab agency partnership efforts pertaining to the design development and execution of all critical market development assets

• Close collaboration with US Market Development Lead as well with ICO counterparts

• Engage with the Global Governance Team (GGT) with a co-creation mindset for designing a launch platform and all assets

• A proven ability to communicate this plan to others responsible for translating Global plans into Regional and Local plans & execution

BASIC QUALIFICATIONS
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers develop and coach others oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

• Bachelors degree required

• 8 years of marketing experience in the pharmaceutical industry oncology and/or global experience is an asset

• Able to collaborate across different functions and interact with others in a way that gains commitment to action ensures clarity and creates common goals

• Strong written oral communication skills coupled with strong analytical skills; able to distill complex data into compelling communications

• Mature self-starter detail-oriented action-driven comfortable with ambiguity; able to multi-task in dynamic environment

• Team player who is patient-focused and focused on Pfizer values: Courage Excellence Equity and Joy by fostering innovation customer focus personal accountability and a commitment for results.

• Demonstrated track record of conducting activities in accordance with company policies and SOPs Pfizer values and regulatory guidelines

OTHER JOB DETAILS:

• Last Date to Apply for Job: February 04 2026

• This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week or more as needed.

Relocation assistance may be available based on business needs and/or eligibility.