Senior Researcher

We currently have an exciting opportunity for aCPRD FTC Senior Researcherto join our Clinical Practice Research Datalink teamin the Safety and Surveillancegroup.

This is afull-time opportunity on a fixed-term contract until 23^rd November 2027. The role will be based in 10 South Colonnade Canary Wharf London E14 4PU. Please be aware that this role can only be worked in the UK and not overseas.

Government departments and agencies are working towards implementing a minimum 60% attendance in office sites.

We are currently implementing a flexible hybrid way of working with a minimum of 4 days per month working on site to enable the collaboration and contact with partners and stakeholders needed to deliver MHRA business. Attendance on site is driven by business needs so depending on the nature of the role this can flex up to 8 days a month with the remainder of time worked either remotely or in the office. Some roles will need to be on site more regularly. Remote working is potentially available for some specific roles. Please discuss this with the recruiting manager before accepting an appointment.

Who are we

The Medicines and Healthcare products Regulatory Agency enhance and improve the health of millions of people every day through the effective regulation of medicines and medical devices underpinned by science and research.

The Safety and Surveillance Group brings together into a single integrated structure devices and medicines safety expertise with enforcement capabilities. These functions will be supported by our data and evidence generating capabilities complementing our signal generating capabilities produced via the new Safety Connect System.

Part of the Safety and Surveillance group The Clinical Practice Research Datalink (CPRD) with support from the National Institute for Health and Care Research (NIHR) is the UKs preeminent research service providing access to anonymised NHS data for addition to supporting high quality observational research CPRD has developed world leading services based on using real world data to support clinical trials and interventional studies.

Whats the role

The CPRD Senior Researcher role offers an exciting opportunity to help shape the UK Governments premier data-driven research service. We are seeking a motivated enthusiastic individual who is interested in an opportunity to participate in and support the delivery of public health research. The Senior Researcher will apply their epidemiological statistical and leadership expertise to a range of studies to develop and deliver CPRD research services. Responsibilities include leadership of commissioned research; characterising validating and integrating new sources of data; monitoring data quality; developing methodologies and algorithms to add value to the data; and providing consultancy and advice to clients using CPRD data and services. The role will also be exposed to novel methods for integrating observational and real-world interventional studies and developing technical solutions for research.

Key responsibilities:

• Develop research services
• Deliver research studies
• Promote CPRD externally and support CPRD clients
• People management

Who are we looking for

Oursuccessful candidatewill have the following:

• A PhD or equivalent experience in epidemiology medical statistics or a related discipline and will have a track record in publishing epidemiological research analysing large electronic health records databases.

• Ensure delivery of timely quality outcomes through providing the right resources to do the job reviewing and adjusting performance expectations and rewarding success.

• Excellent oral and written communication skills with experience in presenting research writing study protocols and drafting strategic papers and manuscripts for publication.

• Experience in data characterisation and developing tools to add value to or analyse complex datasets.

• Knowledge of regulation and governance of using electronic health records for research within the English and devolved administrations legal ethical and governance environments.

Person Specification:

Method of assessment: AApplication IInterview TTest

Behaviour Criteria:

• Delivering at Pace (A I T)

• Working Together (A I)

Experience Criteria:

• Track record in publishing epidemiological research analysing large electronic health records databases. (A I)

• Experience in data characterisation and developing tools to add value to or analyse complex datasets. (A I)

• Excellent oral and written communication skills with experience in presenting research writing study protocols and drafting strategic papers and manuscripts for publication. (A I)

Technical Criteria:

• PhD or equivalent experience in epidemiology medical statistics or a related discipline. (A I T)

• Excellent knowledge of epidemiological and statistical techniques and study design. (A I T)

• In depth understanding of the challenges involved in using electronic health records in public. health research including the use of R and/or Stata. Familiarity with research using primary care data. (A I T)

• Knowledge of regulation and governance of using electronic health records for research within the English and devolved administrations legal ethical and governance environments. (I T)

Strengths Criteria:

• Decisive (I)

• Motivator (I)

If you would like to find out more about this fantastic opportunity please read our Job Description and Person Specification!

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The selection process:

We use the Civil Service Success Profiles to assess our candidatesfind out more here.

• Online application form including questions based on theBehaviour Experience and Technical Success Profiles.Please ensure all application questions are completed in full; your application may not be considered if any responses are left blank. Our applications are CV blind and our Hiring Managers will not be able to access your CV when reviewing your application.

• Test further information will be supplied when you reach this stage

• Interview which can include questions based on theBehaviour Experience Technical and Strengths Success Profiles.

In the instance that we receive a high number of applications we will hold an initial sift based on the lead criteria of:Track record in publishing epidemiological research analysing large electronic health records databases.

Applicants are assessed on whether they meet any mandatory requirements as well as the necessary skills and experience for the role. Applications are scored based on the competency-based answers provided- ensure you have read these thoroughly and allowsufficienttime. You can view the competencies for this role in the job description.

Use of AI in Job Applications

Artificial Intelligence can be a useful tool to support your application however all examples and statements provided must be truthful factuallyaccurateand taken directly from your own experience. Where plagiarism has beenidentified(presenting the ideas and experiences of others or generated by artificial intelligence as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please seeourcandidate guidancefor more information onappropriateand inappropriate use.

If you require any disability related adjustments at any point during the process please contact as soon as possible.

Closing date:Monday 9^th February 2026

Shortlisting date: Thursday 12^th February 2026

Interview date:Thursday 26^th February 2026

Candidates will be contacted within a week of the sift and the interviews completed to inform them of the outcome.

If you need assistance applying for this role or have any other questionsplease contact

Candidates will be subject to UK immigration requirements as well as Civil Service nationality information on whether you are able to apply is availablehere.

Successful candidates must pass a disclosure and barring security check as well as animal rights and pro-life activism checks. People working with government assets must completebasic personnel security standard checks.

Certain roles within the MHRA will require post holders to have vaccinations and in some circumstances routine health surveillance. These roles include:

• Laboratory-based roles working directly with known pathogens

• Maintenance roles particularly those required to work in laboratory settings

• Roles that involve visiting other establishments where vaccination is required

• Roles required to travel overseas where specific vaccination may be required.

Applicants who are successful at interview will be as part of pre-employment screening subject to a check on the Internal Fraud Database (IFD). This check will provide information about employees who have been dismissed for fraud or dishonesty offences. This check also applies to employees who resign or otherwise leave before being dismissed for fraud or dishonesty had their employment continued. Any applicants details held on the IFD will be refused employment. A candidate is not eligible to apply for a role within the Civil Service if the application is made within a 5 year period following a dismissal for carrying out internal fraud against government.

Any move to the MHRA from another employer will mean you can no longer access childcare vouchers. This includes moves between government departments. You may however be eligible for other government schemes including Tax-Free Childcare. Determine your eligibilityhere.

Successful candidates may be subject to annual Occupational Health reviews dependent on role requirements. If you have any queries please contact.

In accordance withthe Civil Service Commissioners Recruitment Principles our recruitment and selection processes are underpinned by the requirement ofselectionfor appointmenton the basis ofmerit by a fair and open competition. If you feel your application has not been treatedin accordance withthe Recruitment Principles and you wish to make a complaint in the firstinstance youshould contact the MHRA Recruitment Team at.

If you are not satisfied with the response you receive you can contact the Civil Service Commission at:

Civil Service Commission

Room G/8

1Horse Guards Road

London

SW1A 2HQ