Senior Scientist, Chemical Research

San Diego, CA - USA

Monthly Salary: $ 105000 - 169050

Posted on: 30+ days ago

Vacancies: 1 Vacancy

Job Summary

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Chemical Research

Job Category:

Scientific/Technology

All Job Posting Locations:

San Diego California United States of America

Job Description:

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at & Johnson Innovative Medicine is recruiting for a Senior Scientist Chemical Research located in San Diego CA.

At Johnson & Johnson Innovative Medicines what matters most is helping people live full and healthy lives. We focus on treating curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science wherever it might be found.

RNA Therapeutics and Delivery is embedded in Cell & Genetic Medicines an organization within Therapeutics Discovery where we are committed to the development of high-quality drug candidates in the Oligonucleotide Therapeutics space working closely with Johnson & Johnson Innovative Medicines Therapeutic Areas (TA) discovery teams. Our mission requires critical thinking a portfolio approach and deep scientific knowledge and expertise in several fields including oligonucleotide chemistry bioconjugation chemistry nanotechnology cellular and molecular pharmacology and screening technologies coupled with an ability to work collaboratively with internal and external partners. This role offers growth opportunity within a dynamic and science driven organization.

Key Responsibilities:

Independently perform solid phase synthesis purification and analysis of oligonucleotides and bioconjugates in a team environment.
Support and trouble-shoot process development efforts for synthesis and characterization of oligonucleotides and their bioconjugates.
In collaboration with the team support oligonucleotide innovation optimization and design for de-risked tissue-specific delivery.
Collect document and evaluate experimental data and communicate scientific findings as verbal presentations and written reports.

Experience and Skills:

PhD or equivalent experience in organic/analytical chemistry chemical biology or related field with 1 year of industry or academic experience in oligonucleotide drug discovery
Hands-on experience with an emphasis on siRNA and/or ASO nucleic acid therapeutics development.
Experience in siRNA synthesis purification and analytical characterization
Experience in siRNA design and chemical modifications
Exposure to the oligonucleotide delivery and drug discovery process
Critical thinking and scientific skills and a demonstrated ability to interpret and clearly communicate data
Strong teammate with the ability to work optimally in a dynamic team environment with diverse views and experiences.
Ability to adapt to changing priorities and timelines

Preferred Qualifications:

Experience in operating instruments and equipment including MerMade and Dr. Oligo synthesizers as well as HPLC LC-MS and UV/Vis purification and characterization instrumentation.
Consistent track record of accomplishments in oligonucleotide research in the form of patents publications and/or presentations at major national meetings.
Knowledge and experience with delivery of oligonucleotides using bioconjugation strategies.
Knowledge of RNA biology and oligonucleotide screening technologies to facilitate effective team collaboration.
Expertise in RNA structure-function studies and molecular modeling as well as characterization of thermodynamic stability of oligonucleotide structures is preferable.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation external applicants please contact us via internal employees contact AskGS to be directed to your accommodation resource.

Required Skills:

Preferred Skills:

Chemistry Collaborating Critical Thinking Data Quality Drug Discovery Development Emerging Technologies Execution Focus Industry Analysis Innovation Interdisciplinary Work Pharmaceutical Trends Pharmacognosy Pharmacology Quantitative Research Research Ethics Scientific Research Technologically Savvy

The anticipated base pay range for this position is :

$105000-$169050

Additional Description for Pay Transparency:

Subject to the terms of their respective plans employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical dental vision life insurance short- and long-term disability business accident insurance and group legal insurance. Subject to the terms of their respective plans employees are eligible to participate in the Companys consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Companys long-term incentive program. Subject to the terms of their respective policies and date of hire Employees are eligible for the following time off benefits: Vacation 120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Washington 56 hours per calendar year Holiday pay including Floating Holidays 13 days per calendar year Work Personal and Family Time - up to 40 hours per calendar year Parental Leave 480 hours within one year of the birth/adoption/foster care of a child Condolence Leave 30 days for an immediate family member: 5 days for an extended family member Caregiver Leave 10 days Volunteer Leave 4 days Military Spouse Time-Off 80 hours Additional information can be found through the link below. Experience:

Senior IC