Cell Line Development Research Associate

Emeryville, CA - USA

Monthly Salary: $ 100 - 115

Posted on: 30+ days ago

Vacancies: 1 Vacancy

Job Summary

Prolific Machinesis ushering in a new era of biotechnology with light. Our mission is to make next-generation therapies broadly available to patients. Our first-of-its-kind Photomolecular Platform uses light to precisely guide how cells produce complex biologics enabling higher titers improved quality and faster development timelines. By helping partners overcome todays manufacturing bottlenecks were accelerating the delivery of life-changing medicines. Prolific is supported by leading investors including Bill Gatess Breakthrough Energy Ventures Mayfield and SOSV.

Help us create a brighter tomorrow with biology. Were looking for mission-driven talented and kind people to join our team.

Prolific Machines is a leading biotechnology company using light to control expression of biotherapeutic proteins to increase titer or improve product quality attributes. We are seeking a motivated candidate to join our Cell Line Development (CLD) team as a Research Associate (RA) or Senior Research Associate (SRA). In this role the ideal candidate will play a crucial part in advancing scientific research delivering pipeline projects improving our Optogenetic Chinese Hamster Ovary (CHO) cells culture and process performance conducting cellular and molecular biology studies to further engineer the CHO Optogenetic cell lines. This role is based on-site in our headquarters in Emeryville CA.

Responsibilities

Conducting experiments independently collecting and analyzing data in a timely manner and maintaining detailed documentation in electronic lab notebooks.
Strong communication skills ability to put the data together and present within the CLD group and across different groups and forums within the company. Ability to quickly analyze and provide critical data and figures to support presentations patent applications or publications.
Collaborate closely with members of the CLD teams as well as other teams within the Prolific Machines Contribute to lab maintenance and safety.
Responsibilities also include developing and optimizing analytical methods ensuring adherence to safety and operational standards following established protocols and providing data for regulatory submissions.
This is a lab-based position and onsite presence is required as dictated by Cell Line Development (CLD) responsibilities and experimental needs.

Qualifications

Education & Experience: A Bachelors degree with 3-6 years of relevant industry experience or a Masters degree with 2-3 years of relevant experience.
Designing and Executing Experiments: Developing and proposing experimental plans conducting experiments and troubleshooting analytical techniques and methodologies
Work Style: The candidate is expected to precisely follow protocols design and execute experiments independently and manage multiple tasks in a fast-paced setting.
Communication Skills: Strong written and verbal communication skills are essential for documenting findings and effective collaboration. Familiarity with Word Excel PowerPoint or similar Google suite software and ability to perform independent data analysis and generating meaningful conclusions is required.

Technical Experience:

Experience with molecular cloning and molecular biology techniques (PCR protein quantification).
Experience with cell line development workflows (pool generation clonal isolation stability testing).
Exposure to high-throughput screening platforms (e.g. Beacon Ambr Octet Automation). Scripting experience on the Tecan would be an added plus.
Working knowledge of statistical analysis or design of experiments (DoE).
Comfort working in a dynamic fast-paced R&D environment.
(Nice to have) Familiarity with optogenetic systems inducible promoters or light-responsive protein engineering.

$85000 - $115000 a year

Starting salary will be dependent upon specific experience knowledge and skillset. The range by level will typically fall between $85k-$100k for RA II and $100k-$115k for Sr. RA.

Benefits:Generous equity package in an early stage company retirement plan with company contribution flexible PTO with healthy time off minimums company-covered medical dental and vision insurance life and disability insurance career coaching mental health support free team lunches everyday great snacks and companywide social events!

Diversity:We value diverse people perspectives and knowledge. To this end we aim to foster a sense of belonging that enables everyone to bring their whole authentic self to work everyday. We are committed to growing a diverse and inclusive team that encompasses all types of people. We believe this can only be achieved by acknowledging the ancestral historic and current systemic and communal inequities.

Required Experience: