Senior Principal Scientist (Modeling), BioTherapeutics Process Development

Malvern, PA - USA

Monthly Salary: Not Disclosed

Posted on: 30+ days ago

Vacancies: 1 Vacancy

Job Summary

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biotherapeutics R&D

Job Category:

Scientific/Technology

All Job Posting Locations:

Malvern Pennsylvania United States of America

Job Description:

About Innovative Medicine:

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at are searching for the best talent for a Senior Principal Scientist (Modeling) BioTherapeutics Process Development to be onsite in Malvern PA.

Purpose:
The API Upstream Process Development Group is searching for a highly qualified and accomplished individual to join the API Upstream Process Development team as a Senior Principal Scientist.

You will lead development and implementation of computational methodologies (modeling) to optimize biotherapeutic processes and cell culture media. You will be part of CMC team(s) and play a significant role in successful delivery of project deliverables. This position is highly cross functional and will require intellectual agility and interpersonal skills to work across different modalities e.g. project teams analytical statistical cell biology and data scientists.

You will be responsible for:

Advancing pipeline by collaborating with multi-functional teams including bioprocess engineers analytical scientist and statisticians
Participating or leading process optimization characterization and/or tech transfer & scale up/down workflow
Serving as a scientific leader in development and implementation of computational modeling methodologies
Developing and embedding advanced data analytics tool for cell culture & media optimization
Contributing to strategic initiatives
Mentoring and upskilling workforce

Qualifications / Requirements:

Education:

Bachelors degree is required
Masters degree or PhD in Chemical Engineering Cell Biology Biochemistry or related fields is highly preferred

Required:

Minimum 8-10 years of biotech/pharmaceutical industry and academic experience
In-depth knowledge of industrial bioprocessing cell culture cell biology and/or system biology
Expertise in process modeling
Expertise in programming languages such as Python R or MATLAB and experience with relevant packages and software tools
Strong project and technical leadership skills demonstrated by successful management and delivery of CMC deliverables
Excellent communication and collaboration skills with the ability to work effectively in a multidisciplinary team
Good written and oral communication skills

Preferred:

Hands-on experience with industrial CMC process development
Hands-on experience or good understanding of metabolic pathways analysis (e.g. MFA/FBA)
Experience/in-depth knowledge of model-based regulatory filings

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation please email the Employee Health Support Center () or contact AskGS to be directed to your accommodation resource.

#LI-Hybrid

Required Skills:

Preferred Skills:

Analytical Reasoning Biochemistry Biotechnology Chemistry Manufacturing and Control (CMC) Clinical Research and Regulations Clinical Trial Designs Collaborating Data Synthesis Drug Discovery Development Molecular Diagnostics Pharmacovigilance Process Improvements Productivity Planning Program Management Scientific Research Tactical Planning Technical Credibility

Required Experience:

Staff IC