Scientist, Analytical Development- LC Method Development

Job Description

Vertex is seeking a talented scientist to join the Analytical Development organization in Boston MA. This individual will help advance transformative medicines by performing analytical chemistry activities through all stages of clinical development. This role is in the Liquid Chromatography Subject Matter Expert (SME) team dedicated to small molecule and synthetic peptide/oligonucleotide LC method development for both drug substances and drug products. The successful candidate will lead LC method development activities for assigned projects participate as a core member in cross-departmental program teams and serve as a technical expert in the space of liquid chromatography.

This is an onsite position.

Key Duties and Responsibilities:

• Develop analytical methods on HPLC/UHPLC with various detection systems (UV QDa CAD etc.) for small molecules and synthetic peptides/oligonucleotides
• Conduct experiments independently following established methodology procedures and SOPs
• Exercise solid judgment to prioritize studies while considering feasibility timelines and project impact
• Independently prepare presentations and presents experimental conclusions at internal or external meetings
• Work collaboratively cross-functionally and within the team to achieve program goals
• Author and review method documents analytical study protocols and reports
• Maintain accurate notebook entries and adhere to governing SOPs
• Perform data verification/review of peer notebooks

Knowledge and skills:

• Design and execution of complex challenging experiments
• Technical expertise in analytical techniques that include HPLC UHPLC IC or LC-MS
• Demonstrated written and verbal communication skills especially in peer-directed presentations and report writing
• Experience in HPLC/UHPLC method development
• Advanced troubleshooting skills and problem-solving capabilities
• Strong analytical data assessment review and interpretation skills
• Ability to work in a fast-paced environment managing priorities and maintaining timelines

Education and Experience:

• Ph.D. (or equivalent degree) and 0-3 years of relevant post-doctoral employment experience in analytical chemistry or the life/physical sciences
• Masters Degree (or equivalent degree) and 3 years of relevant employment experience or
• Bachelors Degree (or equivalent degree) and 6 years of relevant employment experience

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at