Job Description: Quantitative Translational & ADME Sciences Department has an open position for a Scientist III position in North Chicago IL. The successful candidate will be responsible for non-regulated quantitative LC-MS/MS bioanalysis of small molecules from in vivo and in vitro samples including extraction data analysis and interpretation.
Responsibilities: - Perform high throughput quantitative in vivo and in vitro LC-MS/MS analysis troubleshooting and problem solving of small molecule and peptides from various bio-matrices.
- Operate perform routine maintenance and hands-on troubleshooting of AB Sciex LC-MS/MS systems.
- Maintain excellent documentation of all work including LIMS test methods and protocols.
- Work closely with multiple teams across Discovery and DMPK-BA to support bioanalysis.
Requirements: - Bachelors Masters or Ph.D. in Biochemistry Analytical Chemistry or related discipline typically with 8 (BS) 6 (MS) or 0 (PhD) years of relevant academia/pharmaceutical experience.
- Proven method development experience using various extraction chromatographic and analytical methodologies.
- Proven experience with quantitative bioanalysis of small molecules.
- Proven experience operating and troubleshooting Agilent HPLCs Leap/CTC PAL autosamplers and AB Sciex Mass Spectrometers.
- The ideal candidate is detail oriented and committed to generating high-quality results within tight deadlines and across different projects.
- Proven ability to work independently or under minimal supervision in a high-throughput environment to design and conduct experiments interpret document and communicate results as well as in a team environment to collaborate successfully across other groups within R&D.
- Strong communication interpersonal and presentation skills.
- Work experience in regulated bioanalysis and/or CRO Facility settings is a plus.
Key Competencies: - Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
- Learns fast grasps the essence and can change course quickly where indicated.
- Raises the bar and is never satisfied with the status quo.
- Creates a learning environment open to suggestions and experimentation for improvement.
- Embraces the ideas of others nurtures innovation and manages innovation to reality.