Manager IT Infrastructure, Network & Security Operations
Manager IT Infrastructure, Network & Security Operations
Posted on :
19-07-2025
Employer Active
1 Vacancy
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Job Description
Title: Manger IT Infrastructure Network & Security Operations
Manager: Associate Director IT
Department: Information Technology
Location: Richmond CA
Sangamo Therapeutics is a genomic medicine company focused on treating debilitating neurological diseases by using our wholly owned highly versatile zinc finger epigenetic regulation technology and capsid delivery engine. We are passionate about designing and developing genomic medicines to transform the lives of patients suffering from severe diseases with our deep scientific expertise and proprietary zinc finger genome engineering technology. At Sangamo we are dedicated to building a robust sustainable genomic medicine pipeline that addresses life-limiting conditions by replacing todays symptom-focused treatments with tomorrows genomic cures. Our top priority is to meet the needs of patients with commitment and compassion. Along with our commitment to science and to our patients we also endeavor to create an inclusive environment that promotes and values diversity. Sangamo is a company where individuals can flourish grow and develop their expertise.
We are seeking top talent to join our mission. Lets build a better future together.
JOB SUMMARY:
We are seeking a hands-on and strategic IT Manager to lead our infrastructure network and security operations. This role will be responsible for the stability security and performance of both on-premises and cloud-based systems. The ideal candidate will be experienced in system and network architecture cybersecurity practices and automation with a strong understanding of compliance and governance frameworks such as SOX and NIST. This is an onsite role with the flexibility to work remotely according to business and department needs. We are only considering candidates local to the San Francisco Bay Area.
ESSENTIAL FUNCTIONS:
Manager: Associate Director IT
Department: Information Technology
Location: Richmond CA
Sangamo Therapeutics is a genomic medicine company focused on treating debilitating neurological diseases by using our wholly owned highly versatile zinc finger epigenetic regulation technology and capsid delivery engine. We are passionate about designing and developing genomic medicines to transform the lives of patients suffering from severe diseases with our deep scientific expertise and proprietary zinc finger genome engineering technology. At Sangamo we are dedicated to building a robust sustainable genomic medicine pipeline that addresses life-limiting conditions by replacing todays symptom-focused treatments with tomorrows genomic cures. Our top priority is to meet the needs of patients with commitment and compassion. Along with our commitment to science and to our patients we also endeavor to create an inclusive environment that promotes and values diversity. Sangamo is a company where individuals can flourish grow and develop their expertise.
We are seeking top talent to join our mission. Lets build a better future together.
JOB SUMMARY:
We are seeking a hands-on and strategic IT Manager to lead our infrastructure network and security operations. This role will be responsible for the stability security and performance of both on-premises and cloud-based systems. The ideal candidate will be experienced in system and network architecture cybersecurity practices and automation with a strong understanding of compliance and governance frameworks such as SOX and NIST. This is an onsite role with the flexibility to work remotely according to business and department needs. We are only considering candidates local to the San Francisco Bay Area.
ESSENTIAL FUNCTIONS:
- Lead daily IT operations including server network cloud (Azure & AWS) and endpoint environments
- Manage infrastructure security including incident response patch management vulnerability remediation and endpoint protection
- Monitor system performance and ensure high availability scalability and disaster recovery capabilities
- Oversee firewall VPN and network segmentation architecture and operations
- Maintain and optimize AWS cloud resources for cost efficiency and security
- Administer Okta SSO platform for identity and access management
- Manage and oversee external Managed Service Providers (MSPs) to ensure service quality and accountability
- Collaborate with internal teams and vendors to deliver secure scalable and stable IT operations
- Refine and maintain IT operational processes SOPs runbooks and documentation to ensure clarity consistency and audit-readiness
- Ensure compliance with SOX GxP GMP and implement controls aligned with the NIST cybersecurity framework
- Manage Microsoft 365 environment including Exchange Online Azure AD and Microsoft Defender
- Support IT audits risk assessments and quarterly security reporting
- Drive automation efforts using scripting tools (e.g. PowerShell Python)
EDUCATION EXPERIENCE AND SKILLS REQUIREMENTS:
- Bachelors degree in Computer Science Information Technology or equivalent work experience
- 7 years of experience in IT infrastructure networking and/or security operations
- 2 years in a management or team lead capacity
- Experience managing external MSPs and third-party service providers
- Proficient in:
- Windows Server Active Directory DNS/DHCP
- Endpoint management tools (Endpoint Central Action1 Intune)
- Cloud infrastructure (Azure AWS) including cost and performance optimization
- Firewall and VPN technologies (e.g. Palo Alto Cisco)
- Identity and access management tools especially Okta SSO
- Strong experience developing and refining IT processes and standard operating procedures (SOPs)
- Deep understanding of patch management threat remediation and log analysis
- Familiarity with security and compliance frameworks including NIST CSF ISO 27001 and SOX
- Experience implementing or maintaining controls aligned to the NIST framework
PREFERRED SKILLS & QUALIFICATIONS:
- Certifications: CISSP CISM CompTIA Security AWS Certified Solutions Architect Microsoft Certified: Azure Administrator Cisco CCNP
- Familiarity with:
- Microsoft Purview and compliance tools
- Email security tools (e.g. Abnormal Security or similar tools)
- Cybersecurity awareness platforms (e.g. KnowBe4)
- ITSM platforms (e.g. FreshService ServiceNow)
- Generative AI tools and platforms (e.g. Microsoft Copilot Zoom AI Companion ChatGPT)
We believe in the value of diverse perspectives and backgrounds and we welcome candidates who are eager to learn and contribute to our mission. We encourage you to apply even if you dont meet all the qualifications. Share what differentiates you from other candidates.
Sangamo is an equal opportunity employer
Sangamo is committed to fostering belonging for all employees and embraces diversity equity and inclusion in recruiting and hiring. All qualified applicants for employment are encouraged to apply and will be considered without regard to an individuals race color sex gender identity gender expression religion age national origin or ancestry citizenship physical or mental disability medical condition family care status marital status domestic partner status sexual orientation genetic information military or veteran status or any other basis protected by federal state or local laws.
Pay Range
The anticipated salary range is for candidates who will work in our San Francisco Bay Area work locations. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience with the job type and length of experience within the industry education etc. This salary range may not apply to remote positions that work in other states.
Note to External Recruiters: We do not accept unsolicited resumes from any source other than from the candidates themselves. If you wish to be considered for the presentation of candidates please email We will reach out to you directly if there is a business need for your services.
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Required Experience:
Manager
Employment Type
Full Time
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