Key Responsibilities:
- Apply deep domain knowledge in structural biology to characterize macromolecular complexes and understand their roles in disease pathways.
- Integrate structural insights with multi-omics data (genomics transcriptomics proteomics and metabolomics) to understand molecular mechanisms of disease.
- Utilize and develop computational tools for structural modeling molecular dynamics simulations and ligand docking to complement experimental data.
- Stay up to date with the latest advancements in structural biology biophysics and computational methods to incorporate cutting-edge research into disease modeling efforts.
Collaboration & Project Management:
- Work closely with cross-functional teams including disease domain experts computational scientists and clinicians to enhance translational research efforts.
- Work with the Scientific Manager to help in project planning execution and reporting ensuring alignment with research objectives.
- Communicate findings effectively through reports presentations and discussions with internal teams and external collaborators.
- Publish research findings in high-impact peer-reviewed journals.
- Present work at scientific conferences symposia and internal research meetings.
- Contribute to grant applications and funding proposals where relevant.
Qualifications & Experience:
- PhD in structural biology biophysics biochemistry or a closely related field.
- Strong expertise in at least one major structural biology technique (e.g. X-ray crystallography cryo-electron microscopy (cryo-EM) NMR spectroscopy).
- Solid understanding of protein structure-function relationships macromolecular interactions and their relevance to disease biology.
- Experience in experimental design data collection data processing and structure determination.
- Excellent verbal and written communication skills with the ability to convey complex structural biology concepts clearly.
Preferred:
- Experience with computational structural biology tools (e.g. Rosetta AlphaFold molecular dynamics software).
- Previous experience working in a multidisciplinary research environment.
- Familiarity with AI/ML approaches in structural biology or drug discovery.
Other Considerations:
- Fresh PhD graduates will be hired as Postdoctoral Fellows for a two-year term with an opportunity for promotion to Scientist based on performance.
- Candidates with at least two years of postdoctoral experience in structural biology in either academia or industry will be hired as Scientists with opportunities for career advancement.
Education
PG