Real World Evidence Senior Manager Hybrid
Real World Evidence Senior Manager Hybrid
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
Job Description
Job Description
Knowledge and Skills:
Education and Experience:
- The Real World Evidence Senior Manager is an integral member of the RWE team who leverages expertise in epidemiology real world data and other relevant disciplines to assess the natural history and real world outcomes for Vertexs pipeline and portfolio products. The position will support crossfunctional global observational research by providing methodological and analytical support for internal stakeholders including Clinical Development Global Medical Affairs Global Patient Safety and Government Affairs and Public Policy. The Senior Manager will also develop and execute on tactics related to the collection and/or analysis of real world data to inform relevant stakeholders such as regulatory affairs and clinical development.
- Job DescriptionJob Description
General Summary:
The Real World Evidence Senior Manager is an integral member of the RWE team who leverages expertise in epidemiology real world data and other relevant disciplines to assess the natural history and real world outcomes for Vertexs pipeline and portfolio products. The position will support crossfunctional global observational research by providing methodological and analytical support for internal stakeholders including Clinical Development Global Medical Affairs Global Patient Safety and Government Affairs and Public Policy. The Senior Manager will also develop and execute on tactics related to the collection and/or analysis of real world data to inform relevant stakeholders such as regulatory affairs and clinical development.
Key Duties and Responsibilities:
- Lead focused/targeted epidemiologic research in support of Vertexs pipeline and established portfolios including Natural History (NH) of disease and systematic literature reviews
- Ensure scientific rigor and serve as a methodology expert for real world data analyses
- Conduct feasibility assessment of relevant data sources for disease areas and research questions
- Provide expert insights and experience to design and defend fitforpurpose epidemiologic observational research; Select and implement appropriate analytic methods aligned to research needs
- Determine potential utility and feasibility of RWE historical control and/or external controls in support of clinical development programs
- Collaborate with and manage vendors to ensure meeting project timelines and goals
- Support Study Teams for observational studies
- Develop draft study protocol and statistical analyses for review and approval from internal scientific review committees
- Contribute to development of performance metrics and dashboards for RWE projects
- Represent RWE on crossfunctional collaborations and working groups for pipeline product(s)
- Able to balance multiple projects in a fastpaced environment
- Utilize strong oral and visual communication skills and understanding of Vertex strategies to promote and translate value of RWD/RWE methods and studies across the company
- Excellent communication skills (oral and written) with internal and external audiences
- Contribute to company publications strategy via development of conference abstracts presentations peer reviewed manuscripts based on the findings of RWE studies
- Working knowledge of relevant RWE regulatory agency guidance and position papers and the opportunities to use RWE to inform regulatory decision making
- Demonstrated ability to design and execute observational research
- Strong interpersonal communication and study management skills
- Ability to take detailed observational study results and communicate them in a clear non technical manner to internal crossfunctional teams using language that resonates with the teams while maintaining the integrity of key findings
- Ability to work collaboratively in a constantly changing diverse and matrix environment
- PhD (preferred) or MS/MPH in epidemiology biostatistics health economics and outcomes research or similar required
- Formal graduate training in Epidemiology/Health Services Research required
- Minimum 3 years of experience working in observational research within the life sciences industry or relevant academic government or consulting environment
- Minimum 1 year of experience working in RWE and/or Epidemiology at a biopharmaceutical company
#LIAR1
#LIHYBRID
Pay Range:
$169500 $254200Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors including skills competencies experience and other jobrelated factors permitted by law.
At Vertex our Total Rewards offerings also include inclusive marketleading benefits to meet our employees wherever they are in their career financial family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical dental and vision benefits to generous paid time off (including a weeklong company shutdown in the Summer and the Winter) educational assistance programs including student loan repayment a generous commuting subsidy matching charitable donations 401(k) and so much more.
Flex Designation:
HybridEligible Or OnSite EligibleFlex Eligibility Status:
In this HybridEligible role you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. OnSite: work five days per week onsite with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and nondiscrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an EVerify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at
Required Experience:
Senior Manager
Employment Type
Full-Time
