Principal Scientist Downstream Biologics Process RD
Principal Scientist Downstream Biologics Process RD
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$ 169700 - 267200
1 Vacancy
Job Description
Job Description
BPR&D Downstream Principal Scientist
Job Description:
Our Scientists are our Inventors. Using innovative thinking stateoftheart facilities cuttingedge science and technology we partner to deliver the next medical breakthrough. We are seeking a collaborative selfdirected learner with a penchant for problemsolving and expertise in downstream bioprocessing to join Biologics Process Research & Development (BPR&D) as a Principal Scientist.
BPR&D within our companys Research Laboratories is on a mission to rapidly deliver diverse biotherapeutics to patients by efficiently developing innovative robust manufacturing processes and technologies. To achieve this we work closely with colleagues in Discovery Preclinical Early Development Analytical Formulation and Commercial Manufacturing while providing a diverse and inclusive environment for all. Beyond process development for pipeline biologics we innovate and build next generation biomanufacturing technologies. Examples include investments for development of continuous manufacturing green and sustainable processes and proprietary technology platforms. We actively publish and engage with the scientific community to influence the field.
As a Principal Scientist you will have the opportunity to influence the future direction of our companys Downstream Processing of Biologics. You will work with an immensely creative and collaborative team of scientists and engineers to design purification processes while developing technical strategies related to downstream processing for drug candidates in early and latestage development.
Responsibilities include but are not limited to:
As an impactful contributor shape and realize innovation across the Biologics pipeline strategy and science
Advance the pipeline by collaborating with crossfunctional teams from Research & Manufacturing in a fastpaced multidisciplinary environment
Participate in or lead 1 development of robust and scalable purification processes for biologics in different stages of clinical development 2 process characterization and regulatory filings for successful commercialization
Advance downstream processes by improving efficiency and cost effectiveness through research and innovation while assessing technologies and industry best practices
Collaborate with academia industry and vendors to drive development and early adoption of novel process technologies
Contribute to strategic initiatives; partner with senior leaders to set overall project strategy and guide teams towards its execution
Conceptualize plan and execute projects with effective organizational prioritization and problemsolving skills
Stay abreast of scientific and regulatory landscape; actively present (premier conferences) publish (peerreviewed journals) and patent
Represent BPR&D as a downstream bioprocess expert in internal crossfunctional project teams and external conferences/consortia
Mentor and actively share expertise; guide career development; build strong collaborative teams
Champion compliance and safety; promote a culture of diversity inclusion and equity
MINIMUM EDUCATION REQUIREMENTS:
Ph.D. with 6 years MS with 8 years or BS with 10 years of industry experience and background in Chemical/Biochemical engineering or a related field
REQUIRED EXPERIENCE SKILLS AND COMPETENCIES
Strong fundamental knowledge and subject matter expertise in downstream processing of biologics recent advances and challenges in the field
Expertise in independently conducting and directing the design analysis and documentation of all stages of purification process development
Track record of accomplishments in downstream bioprocessing with a history of peerreviewed publications and presentations
Knowledge of biologics CMC development
Adaptability and agility to prioritize and deliver complex objectives often on tight timelines in a rapidly changing environment
Experience and aptitude to lead work and collaborate in internal and external crossfunctional matrixed teams
Actionoriented mindset for creativity; ability to take initiative innovate iterate and problemsolve
Demonstrated commitment to coach and mentor staff to maximize talent development and utilization
Excellent interpersonal and communication skills
PREFERRED EXPERIENCE & SKILLS:
Leadership of CMC development teams
Continuous biomanufacturing integrated with processanalytical technologies
Highthroughput experimentation automation and process control
Knowledge of protein expression analytics conjugation chemistry and formulation
Biophysical mechanistic and facility modeling; statistical analysis datascience machine learning artificial intelligence
#BPRD #PRD
Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
Our company is committed to inclusion ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
As an Equal Employment Opportunity Employer we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race color age religion sex sexual orientation gender identity national origin protected veteran status disability status or other applicable legally protected a federal contractor we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws visit:
We are proud to be a company that embraces the value of bringing together talented and committed people with diverse experiences perspectives skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas broad experiences backgrounds and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one anothers thinking and approach problems collectively.
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U.S. Hybrid Work Model
Effective September 5 2023 employees in officebased positions in the U.S. will be working a Hybrid work consisting of three total days onsite per week Monday Thursday although the specific days may vary by site or organization with Friday designated as a remoteworking day unless business critical tasks require an onsite Hybrid work model does not apply to and daily inperson attendance is required for fieldbased positions; facilitybased manufacturingbased or researchbased positions where the work to be performed is located at a Company site; positions covered by a collectivebargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note this Hybrid work model guidance also does not apply to roles that have been designated as remote.
The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors which may include but not be limited to the primary work location and the chosen candidates relevant skills experience and education.
Expected US salary range:
$169700.00 $267200.00Available benefits include bonus eligibility long term incentive if applicable health care and other insurance benefits (for employee and family) retirement benefits paid holidays vacation and sick days. A summary of benefits is listed here.
San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only:We will consider for employment all qualified applicants including those with criminal histories in a manner consistent with the requirements of applicable state and local laws including the City of Los Angeles Fair Chance Initiative for Hiring Ordinance
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Merck & Co. Inc. Rahway NJ USA also known as Merck Sharp & Dohme LLC Rahway NJ USA does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no preexisting agreement is in place. Where agency agreements are in place introductions are position specific. Please no phone calls or emails.
Employee Status:
RegularRelocation:
DomesticVISA Sponsorship:
YesTravel Requirements:
10Flexible Work Arrangements:
Not ApplicableShift:
Not IndicatedValid Driving License:
NoHazardous Material(s):
n/aJob Posting End Date:
05/2/2025*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Required Experience:
Staff IC
Employment Type
Full-Time
