Postdoctoral Fellow - T cell and B cell biology in cancer
Postdoctoral Fellow - T cell and B cell biology in cancer
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Salary Not Disclosed
1 Vacancy
Job Description
Overview
The Keith Syson Chan laboratory4cure/has assembled a highly supportive research environment for trainees and is seeking a selfmotivated career goaldriven postdoc (at all levels) with enthusiasm to identify novel immune checkpointsand/or investigate how adaptive immune response can be leveraged for therapies Nature517: ;Nature Communications10:;Nature Communications11:;Nature Communications13:; J Natl Cancer Inst.:;Nature Reviews Urology19: . We have established tumor models representing hot and cold tumors with scRNAseq profiling and corresponding differential response to immune checkpoint blockade therapy. These data and models will be used as the foundation for project mining and experimental investigations. Our lab also has inlab flow cytometry analyzer and sorter spatial biology platforms (e.g. 10X Xenium 10X CytAssist Akoya PhenoCycler etc) proteomics profiling capacity and ample fundings to integrate omics data with functional assays for research investigations. Candidates are highly welcome to bring their own ideas those with at least one first author publication and expertise in T cell or B cell biology or one of following research topics are highly encouraged to apply:
- T/B cell development T/B cell receptor repertoire sequencing
- Cancer immunology and the immune TME
- Immunometabolism
- Mechanisms of immune exclusion and checkpoint resistance
- Secondary (e.g. lymph node) and tertiary lymphoid structure biology
- Therapeutic antibody evaluation
Postdoc candidates receive equal benefits as fulltime Methodist employees.
Houston Methodist Standard
PATIENT AGE GROUP(S) AND POPULATION(S) SERVED
Refer to departmental Scope of Service and Provision of Care plans as applicable for description of primary age groups and populations served by this job for the respective HM entity.
HOUSTON METHODIST EXPERIENCE EXPECTATIONS
- Provide personalized care and service by consistently demonstrating our I CARE values:
- INTEGRITY: We are honest and ethical in all we say and do.
- COMPASSION: We embrace the whole person including emotional ethical physical and spiritual needs.
- ACCOUNTABILITY: We hold ourselves accountable for all our actions.
- RESPECT: We treat every individual as a person of worth dignity and value.
- EXCELLENCE: We strive to be the best at what we do and a model for others to emulate.
- Practices the Caring and Serving Model
- Delivers personalized service using HM Service Standards
- Provides for exceptional patient/customer experiences by following our Standards of Practice of always using Positive Language (AIDET Managing Up Key Words)
- Intentionally collaborates with other healthcare professionals involved in patients/customers or employees experiential journeys to ensure strong communication ease of access to information and a seamless experience
- Involves patients (customers) in shift/handoff reports by enabling their participation in their plan of care as applicable to the given job
- Actively supports the organizations vision fulfills the mission and abides by the I CARE values
Responsibilities
PEOPLE ESSENTIAL FUNCTIONS
- Assists the physician in maintaining the functionality and operations of the Principal Investigators (PI) laboratory.
- Promotes a positive work environment and leads the team to be dynamic and a focused work unit that actively helps one other to achieve optimal department results. Collaborates with all members of the department by actively communicating and reporting data in a comprehensive manner.
- Role models to team members effective verbal nonverbal and written communication which includes active listening and teaching assisting in development of such skills.
- Provides contributions towards improvement of department scores for employee engagement i.e. peertopeer accountability.
SERVICE ESSENTIAL FUNCTIONS
- Develops research methods and performs research activities.
- Documents research results and writes reports of results for presentation and/or publication in professional journals and other publications.
QUALITY/SAFETY ESSENTIAL FUNCTIONS
- Follows all safety rules while on the job. Reports accidents promptly and corrects minor safety hazards. Communicates with peers and management regarding any hazards identified in the workplace.
- Assists with implementation and education of departmentbased safety initiatives standards of practice and protocols. Develops skills of team members and continually assists with improving skills performance and outcomes.
- Identifies opportunities for corrective action and process improvement providing recommendations and contributes to meeting department and laboratory targets for quality and safety.
FINANCE ESSENTIAL FUNCTIONS
- Utilizes resources effectively and efficiently demonstrating responsible financial stewardship. Manages own time effectively and prioritizes work to achieve maximum results in a timely manner.
- Uses resources efficiently; does not waste supplies. Selfmotivated to independently manage time effectively and prioritize daily tasks.
GROWTH/INNOVATION ESSENTIAL FUNCTIONS
- Participates in pertinent research activities and evidencedbased practice projects. Participates in departmental projects and activities. Acts as a change agent.
- Seeks opportunities to expand learning beyond baseline competencies with a focus on continual development. Remains current on professional issues and clinical skills. Completes and updates the My Development Plan on an ongoing basis. Ensures own career discussions occur with appropriate management.
This job description is not intended to be allinclusive; the employee will also perform other reasonably related business/job duties as assigned. Houston Methodist reserves the right to revise job duties and responsibilities as the need arises.
Qualifications
EDUCATION
- Postdoctoral Fellow 0 1 2 3 4 Doctor of Medicine (MD) from an accredited medical school or Terminal Degree in a related field (A letter from the academic institution certifying that all student work is complete will be considered for Postdoctoral Fellow 0 only.
WORK EXPERIENCE
- Postdoctoral Fellow 0 None
Postdoctoral Fellow 1 One year of Postdoc experience
Postdoctoral Fellow 2 Two years Postdoc experience
Postdoctoral Fellow 3 Three years Postdoc experience
Postdoctoral Fellow 4 Four years Postdoc experience
License/Certification
LICENSES AND CERTIFICATIONS REQUIRED
- N/A
KSA/ Supplemental Data
KNOWLEDGE SKILLS AND ABILITIES
- Demonstrates the skills and competencies necessary to safely perform the assigned job determined through ongoing skills competency assessments and performance evaluations
- Sufficient proficiency in speaking reading and writing the English language necessary to perform the essential functions of this job especially with regard to activities impacting patient or employee safety or security
- Ability to effectively communicate with patients physicians family members and coworkers in a manner consistent with a customer service focus and application of positive language principles
- Demonstrated knowledge of biomedical research
- Ability to work effectively in a fastpaced environment
- Demonstrates flexibility and adaptability in the workplace
SUPPLEMENTAL REQUIREMENTS
WORK ATTIRE
- Uniform No
- Scrubs Yes
- Business professional No
- Other (department approved) Yes
ONCALL*
*Note that employees may be required to be oncall during emergencies (ie. DIsaster Severe Weather Events etc) regardless of selection below.
- On Call* No
TRAVEL**
**Travel specifications may vary by department**
- May require travel within the Houston Metropolitan area No
- May require travel outside Houston Metropolitan area No
Company Profile
Houston Methodist Research Institute was formed in 2004 to rapidly and efficiently translate discoveries made in the laboratory and the clinic into new diagnostics therapies and treatments. The research institute was created to provide the infrastructure and support for these endeavors and to house the technology and resources needed to make innovative breakthroughs in important areas of human disease. A 540000 square foot building dedicated to research the research institute houses over 1500 staff and trainees 284 principal investigators and has more than 570 ongoing clinical trials.
Employment Type
Full-Time
