Senior Principal ScientistAssociate Director Translational Development Lung Cancer Disease Lead
Senior Principal ScientistAssociate Director Translational Development Lung Cancer Disease Lead
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Job Description
Working with Us
Challenging. Meaningful. Lifechanging. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here uniquely interesting work happens every day in every department. From optimizing a production line to the latest breakthroughs in cell therapy this is work that transforms the lives of patients and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope alongside highachieving teams. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits services and programs that provide our employees with the resources to pursue their goals both at work and in their personal lives. Read more: Medicine at BMS
Translational medicine is a department within the Research organization that facilitates the transition of drug candidates from early to latestage clinical development their approval and life cycle management. Earlystage translational development activities enable rational determination of doseschedule and responsive patient populations based on deep understanding of drug mechanism of action and disease segments.
Latestage translational development activities build upon the early work additionally exploring mechanisms of resistance rational drug combinations and product differentiation. The latestage Translational Development function is responsible for the development of translational strategies to support the development and maximize the potential of BMSs therapies postclinical proofofconcept including registrations and lifecycle management.
Translational disease strategies in solid tumor oncology are derived from long term investments in developing data and deep expertise in disease biology patient segments immunodeficiencies and of therapeutic resistance to assist science driven strategies for the development of the oncology pipeline.
Summary
Reporting to the Solid Tumor Lung Disease Head in Translational Medicine the incumbent will be part of the translational group and will help develop translational disease strategies in lung cancer across multiple asset programs for approval or lifecycle management in the BMS pipeline. Key responsibility of this role is to effectively collaborate with a cross functional team of asset scientists with deep disease drug development and business knowledge to help drive an overall translational strategy working closely with discovery and early development teams late clinical development as well as with our team of laboratory scientists.
Position Description:
Develops and executes translational disease strategy in lung disease area with deep disease expertise
Leads and oversees of disease strategy including but not limited to various aspects of patient selection strategies
Serves as scientific expert in generating novel hypotheses for targetable biologies based on novel discoveries integrating disease work with literature and deep expertise in lung biology
Manages cross functional disease project teams with key interfaces in IT bioinformatics data sci stats external collaborators contractors other disease strategy leads and asset leads
Maintains relationship with translational clinicians for identifying new opportunities and for gaining disease insight
Identifies needs gaps and translational disease questions and applies knowledge across all assets in BMS portfolio in lung area
Leads small and large collaborations with academia and industry partners to identify biobanks clinical trials and existing databases to collate multiparameter genomic immune and clinical datasets to mine for novel biomarkers of unmet need patients in conjunction with computational biologists data scientists and statisticians
Collaborate and guide bioinformatics partners on biological questions to deliver biomarkers and biological understanding from whole transcriptome whole exome and/or whole genome data immune profiling and single cell data in order to support drug discovery and development in solid tumor oncology.
Manage relationships with key internal stakeholders including regulatory clinical and commercial and scientific communications and external collaborators to develop translational analysis plans and timelines communicate analysis results.
Represent the Solid Tumor Oncology Translational Development function at various internal meetings and provide domain knowledge and disease expertise to crossfunctional teams.
Direct and support publications in high quality scientific technical or medical journals.
Qualifications:
PhD degree in a relevant field (e.g. molecular biology cancer biology human genetics immunology).
Minimum of 6 years postPhD experience for Sr. Principal Level (and minimum of 8 years PostPhD experience for AD Level) with demonstrated scientific leadership in integrating analyzing and interpreting multimodal biological data in an academic and/or industry setting.
Strong background in human genetics/genomics cellular biology immunology or immunooncology with an understanding of the tumor microenvironment is required.
Extensive knowledge of highcontent biomarker platforms and good understanding of the current clinical practice in early and late stage lung cancer
Ability to work in a fastpaced environment with rapidly changing and competing priorities and ambiguity.
Strong team player with the ability to work in crossfunctional teams. Excellent communication and collaboration skills.
Prior experience with clinical trials preferred
Strong track record of highquality scientific publications in relevant fields
#LIHybrid
If you come across a role that intrigues you but doesnt perfectly line up with your resume we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work Lifechanging Careers
With a single vision as inspiring as Transforming patients lives through science every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture promoting global participation in clinical trials while our shared values of passion innovation urgency accountability inclusion and integrity bring out the highest potential of each of our colleagues.
Onsite Protocol
BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes siteessential sitebydesign fieldbased and remotebydesign jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Siteessential roles require 100 of shifts onsite at your assigned facility. Sitebydesign roles may be eligible for a hybrid work model with at least 50 onsite at your assigned facility. For these roles onsite presence is considered an essential job function and is critical to collaboration innovation productivity and a positive Company culture. For fieldbased and remotebydesign roles the ability to physically travel to visit customers patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application or in any part of the recruitment process direct your inquiries to . Visit to access our complete Equal Employment Opportunity statement.
BMS cares about your wellbeing and the wellbeing of our staff customers patients and communities. As a result the Company strongly recommends that all employees be fully vaccinated for Covid19 and keep up to date with Covid19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area.
If you live in or expect to work from Los Angeles County if hired for this position please visit this page for important additional information: data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
Required Experience:
Director
Employment Type
Full-Time
