Research Scientist Small Scale Antibody Production and Automation
Research Scientist Small Scale Antibody Production and Automation
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Job Description
Description:
We are looking for a confident and driven Research Scientist (or Associate) with a passion for innovation and a desire to make a meaningful impact in antibody production. Join our SmallScale Antibody Production and Automation team within the Antibody Production Sciences (APS) group part of the Antibody and Novel Therapeutics (ANT) department.
In this role you will contribute to the development of cuttingedge therapeutic and tool antibody reagents supporting projects from earlystage discovery through to latestage preclinical evaluation. This is an exciting opportunity to work with a dynamic multidisciplinary team and take on a role that combines handson laboratory work with datadriven approaches to innovation.
If you are eager to develop automation technologies explore machine learning solutions for data analysis and apply cuttingedge techniques in antibody production we encourage you to apply.
Key Responsibilities
Perform smallscale transient mammalian transfections and purify monoclonal antibodies using automated techniques.
Troubleshoot purification and quality issues interpret data and propose creative solutions to ensure the delivery of highquality reagents.
Lead and support the development optimisation and implementation of automated/robotic highthroughput platforms for antibody expression and purification.
Apply data analysis and visualisation tools to improve workflows and troubleshoot bottlenecks.
Collaborate with crossfunctional teams (Discovery Sciences Process Development Analytical Characterisation) to ensure timely communication of progress issues and solutions.
Explore opportunities to integrate machine learningbased predictive tools into workflows enhancing the quality and efficiency of processes.
Maintain diligent and accurate experimental records using electronic laboratory notebooks and online registration systems.
Ensure lab equipment is maintained to high standards including assisting with cleaning calibration and upgrades.
Requirements
Essential Qualifications and Experience
Bachelor s or Master s degree in Biochemistry Biotechnology or related fields.
Proven experience in cell culture antibody expression purification or characterisation.
Strong understanding of protein biochemistry purification techniques and analytical methods.
Desirable Skills and Attributes
Industrial experience in a relevant field is highly advantageous.
Expertise in mammalian cell culture (CHO HEK) including aseptic techniques and maintaining cell stocks.
Proficiency with antibody/protein purification systems such as AKTA and Unicorn software.
Familiarity with automation and robotics for highthroughput purification workflows.
Interest in or experience with machine learning software for data analysis and optimisation of processes.
Practical knowledge of protein characterisation techniques: SEC SDSPAGE Western blotting and UVVis spectroscopy.
Competence in using data management systems including Excel logistics databases and sample tracking systems.
What We Offer
The chance to work on highimpact antibodybased therapeutic projects advancing into the clinic and beyond.
A collaborative innovative environment where your contributions will directly shape outcomes.
Opportunities to explore and apply automation technologies and machine learning tools to advance antibody production workflows.
Access to cuttingedge equipment and platforms with ample room for skill development and growth.
Additional Notes
This role is ideal for a scientist who is:
Proactive curious and motivated to solve challenges with innovative solutions.
Excited to push boundaries in antibody production while leveraging automation and datadriven approaches.
Confident in their ability to work independently and as part of a multidisciplinary team.
Essential Qualifications and Experience Bachelor s or Master s degree in Biochemistry, Biotechnology, or related fields. Proven experience in cell culture, antibody expression, purification, or characterisation. Strong understanding of protein biochemistry, purification techniques, and analytical methods. Desirable Skills and Attributes Industrial experience in a relevant field is highly advantageous. Expertise in mammalian cell culture (CHO, HEK), including aseptic techniques and maintaining cell stocks. Proficiency with antibody/protein purification systems such as AKTA and Unicorn software. Familiarity with automation and robotics for high-throughput purification workflows. Interest in or experience with machine learning software for data analysis and optimisation of processes. Practical knowledge of protein characterisation techniques: SEC, SDS-PAGE, Western blotting, and UV-Vis spectroscopy. Competence in using data management systems, including Excel, logistics databases, and sample tracking systems. What We Offer The chance to work on high-impact antibody-based therapeutic projects advancing into the clinic and beyond. A collaborative, innovative environment where your contributions will directly shape outcomes. Opportunities to explore and apply automation technologies and machine learning tools to advance antibody production workflows. Access to cutting-edge equipment and platforms, with ample room for skill development and growth. Additional Notes This role is ideal for a scientist who is: Proactive, curious, and motivated to solve challenges with innovative solutions. Excited to push boundaries in antibody production while leveraging automation and data-driven approaches. Confident in their ability to work independently and as part of a multidisciplinary team.
Employment Type
Full Time
