Senior Scientist - Structural Bioinformatics Research

At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through (link removed) oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.


CITRE, based in Seville, Spain, is Bristol Myers Squibbs research institute in Europe, and our link to the European research community.

Informatics & Predictive Sciences at CITRE performs innovative computational research to inform decisions across all stages of drug development. Areas of research include computational and network biology, machine/deep learning, cheminformatics, predictive modeling, patient stratification, and method development for analysis and interpretation of biological data.

We are looking for an enthusiastic, creative and collaborative
Senior Scientist, Structural Bioinformatics Research
to join us in facing challenging scientific problems head-on and demonstrating how computational research can transform the lives of patients.

The successful candidate will:
Join a multi-disciplinary team to contribute in both technical and scientific aspects at the interface between biology, chemistry and machine learning.
Participate in research projects involving cutting-edge therapeutical strategies such as gene-therapy, targeted protein degradation and other groundbreaking developments of enormous potential.
Innovate through the application, development, and integration of state-of-the-art deep learning models to further understand relevant biomolecular interactions with a strong emphasis on interpretability at the molecular structure level.
Actively collaborate with scientific teams of different backgrounds and locations.
Creatively identify opportunities to apply or develop predictive approaches that contribute to the data-driven understanding of mechanisms of action and indications.

Requirements:
PhD in a relevant discipline, such as biochemistry, computer science, biophysics or related fields, accompanied by original research publications. Additional industry or postdoctoral research experience will be valued very positively.
Expertise in scripting/programming (e.g. R, Python, C++), data analysis and biological interpretation regarding molecular data (e.g. protein 3D structures, sequence, compound SMILES, etc).
Experience in applying or developing machine/deep learning models in the context of 3D macromolecular structures (CNNs, VAEs, graphs, etc), ideally considering aspects of molecular flexibility, dynamics and conformational change.
Attention to detail and capacity to communicate technical/scientific concepts clearly and concisely to audiences of varied backgrounds.
Verbal and written English language fluency.



Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.