Temp Sr. Research Associate DMPK
Redwood City, CA - USA
Job Summary
Revolution Medicines is a global commercial-state oncology company dedicated to discovering developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform the company is advancing a broad integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active cancer-driving state of on rigorous scientific inquiry and a willingness to challenge long-held assumptions Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.
Our people are united by a shared way of working: follow the science challenge assumptions act with urgency and hold ourselves to a high standard of rigorall in service of patients.
The Opportunity:
Develop LC-MS/MS methods and analyze in vivo and in vitro samples to support ADME pharmacokinetic and toxicokinetic studies etc.
Handle a variety of tissues including tumors from tissue homogenization through sample preparation for bioanalysis.
Perform data analysis prepare experimental result reports and upload data to electronic notebooks.
Conduct in vitro ADME/DMPK assays in biological matrices including hepatocytes microsomes blood and plasma ect.
Support laboratory operations including LC-MS/MS instrument maintenance and troubleshooting.
Required Skills Experience and Education:
Bachelors or masters degree in pharmaceutical sciences or a related scientific discipline with 5 years of industry experience for bachelors degree holders or 3 years for masters degree holders.
Hands-on experience in operating and maintaining LC-MS/MS systems.
Hands-on experience in LC-MS/MS method development and bioanalytical analysis.
Knowledge of biological sample preparation and extraction techniques for downstream LC-MS/MS analysis.
Hands-on experience in HPLC/UPLC method development.
Ability to customize and follow established assay protocols.
Ability to manage multiple laboratory and project tasks efficiently.
Ability to work effectively in a flexible team-oriented environment.
Highly organized and detail-oriented with excellent recordkeeping skills and the ability to adapt to a dynamic fast-paced environment.
Preferred Skills:
Previous hands-on experience in SCIEX QTRAP and Thermo Q Exactive mass spectrometers.
Previous hands-on experiences on bioanalytical method development in compliance with regulatory requirements.
Working experience in DMPK lab.
The base salary range for this full-time position is $xxx to $xxx for candidates working onsite at our headquarters in Redwood City CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role level and location. Individual pay is determined by multiple factors including job-related skills experience market dynamics and relevant education or training.
Please note that base salary is one part of the overall total rewards program at RevMed which includes competitive cash compensation robust equity awards strong benefits and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race color religion gender sexual orientation gender identity/expression national origin/ancestry age disability marital status medical condition and veteran status.
Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect process and use any personal data that you provide to us in accordance with ourCCPA additional information please contact.
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Required Experience:
Senior IC
About Company
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, ... View more