Structural Biologist III
Aliso Viejo, CA - USA
Job Summary
Compensation:
$120000 - $170000
Role Overview
The Structural Biologist III collaborates across biology bioinformatics software engineering and clinical teams to design tools and methodologies leveraging biomolecular structural data to guide clinical decisions.
Key Responsibilities
Provide structural biology support for variant analyses through structure-function relationship interpretation.
Develop novel methods protocols and tools for structural modeling molecular dynamics and clinical variant assessment on internal platforms.
Partner with statisticians and data scientists to validate algorithms and data collection workflows.
Coordinate cross-functional efforts across Bioinformatics R&D and reporting teams for clinical research projects.
Write testable production-grade code adhering to SDLC standards and code review best practices.
Maintain technical documentation SOPs and knowledge bases while mentoring junior staff.
Direct and lead the structural team through both soft and explicit leadership ensuring timely project completion
Support inform and educate leadership and stakeholders about project progress and blockers.
Qualifications & Competencies
Education: PhD in computational biology structural biology biophysics bioinformatics or equivalent.
Experience: Minimum 5 years of R&D experience in computational structural biology or related fields including at least 2 years of post-doctoral or industrial experience and 2 years management experience.
Technical Skills: Fluency/proficiency in scripting/languages (Python R Perl C/C Java SQL) and bioinformatics/modeling software. Strong background in systems biology molecular dynamics and experimental techniques (X-ray Cryo-EM).
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Required Experience:
IC
About Company
Ambry delivers high-quality, accessible genetic testing for hereditary cancer and exome sequencing for rare disease. A trusted lab for 25 years.