Staff Mechanical Engineer

Changing the definition of sequencing isnt just our tagline its a commitment to game-changing advances in the field of genomics. Fueled by equal parts scientific vision and determined passion we are delivering unprecedented innovation to short-read sequencing technologies and transforming how genomic information is accessed. You will feel the 10x difference the moment you enter our offices and labs. Theres a dynamic energy here and were looking for the best of the best to be a part of it. We are seeking talented professionals excited to build new technology that advances scientific research while growing their career within a dynamic supportive environment.

As a Staff Mechanical Engineer at 10x Genomics you will take on full leadership of critical projects and teams. You will serve as a technical expert and thought leader within the mechanical engineering function wielding significant influence over both the strategy and execution of complex high-impact mechanical this role you will guide the development of cutting-edge mechanical technologies for breakthrough spatial biology applications play a central role in mentoring and growing the engineering team and drive process innovations that contribute directly to the companys product pipeline and long-term mission.

• Strategic Mechanical Design: Lead the architecture and design of large-scale mechanical systems and critical subsystems for complex biotech devices. Drive multi-disciplinary integration across mechanical fluidic electrical optical and software domains.
• Biotech Innovation: Lead the development of novel mechanical approaches to solve complex problems in genomics (e.g. bioprocessing systems automation platforms liquid handling and consumables). Explore and implement emerging technologies like robotics advanced automation or novel fabrication methods.
• Regulatory & Environment Compliance: Ensure all designs meet rigorous technical performance and regulatory standards.
• Advanced Modeling & Simulation: Utilize advanced simulation tools (such as FEA CFD and multi-body dynamics) to predict system behavior under operational conditions design for failure modes and optimize complex mechanical parts and assemblies.

• End-to-End Project Ownership: Take full ownership of critical mechanical design projects from initial concept prototyping and testing through to manufacturing and final deployment. Develop comprehensive project plans managing timelines and deliverables.
• Design for Manufacturability (DFM): Work closely with NPI Manufacturing and Service teams to optimize designs for scalability and reliability. Perform DFMEAs and identify research and collaborate with strategic external vendors and suppliers.
• Process Improvement: Propose and implement new engineering tools testing methodologies or design workflows to optimize team efficiency reduce cycle times and cut development costs without sacrificing quality.

• Cross-Functional Team Leadership: Lead and influence cross-functional teams (including Chemistry Molecular Biology Software and Electrical Engineering) to ensure seamless system integration.
• Executive & External Representation: Act as the primary technical representative for mechanical engineering. Present complex data technical risks and strategic recommendations to senior leadership.
• Team Development & Mentorship: Mentor and develop a high-performing team of engineers. Foster an inclusive growth-oriented culture provide career development guidance and actively assist in recruitment efforts.
• IP Generation: Identify opportunities to patent new technologies or design approaches actively preparing and reviewing patent submissions to establish a competitive market advantage.

• Education & Experience: BS/MS/Ph.D. in Mechanical Engineering with a minimum of 10 years of relevant industry experience within biotech medical devices robotics or high-tech instrumentation.
• Technical Mastery: Deep theoretical fundamentals in kinematics/dynamics thermals materials selection (plastics metals) fluidics and stress analysis.
• CAD & Simulation Proficiency: High proficiency in 3D CAD design and surfacing (SolidWorks and EPDM/PDMWorks preferred). Advanced expertise in Finite Element Analysis (FEA) and tolerance analysis.
• System Integration: Proven experience managing complex electromechanical assemblies containing motors actuators pumps valves regulators sensors cameras and temperature controllers.
• Product Lifecycle Knowledge: Thorough understanding of all phases of the product development lifecycle including design control processes (specifications design reviews risk analysis) transfer to manufacturing and field reliability tracking.

• Exceptional written and verbal communication skills with a proven ability to distill complex technical data for executive-level presentations.
• Demonstrated experience in at least two of the following specialized areas: control systems dynamics/kinematics mass flow/thermodynamics optical systems or fluidic handling.
• Prior experience establishing a culture of innovation driving patent submissions or acting as an industry thought leader through publications or speaking engagements.
• Hands-on experience with machining prototyping and operating machine shop equipment.
• Familiarity with electronic document control systems (ECO processes).
• Basic knowledge of software programming or electrical engineering design to better facilitate cross-functional collaboration.
• High energy a hands-on can-do approach and a strong interest in working within a fast-paced dynamic environment.

Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate including ones skills qualifications and experience. At 10x base pay is also just one component of the Companys total compensation package. This role is also eligible for 10xs equity grants its comprehensive health and retirement benefit programs and its annual bonus program or sales incentive program. During the hiring process your 10x recruiter can share more about the Companys total compensation package.

Pay Range

About 10x Genomics

At 10x Genomics accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer immunology and neuroscience.

Our teams are empowered and encouraged to follow their passions pursue new ideas and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies better treatments and a better future. Find out how you can make a 10x difference.

Individuals seeking employment at 10x Genomics are considered without regards to race color religion national origin age sex marital status ancestry physical or mental disability veteran status gender identity or sexual orientationor any other characteristic protected by applicable law.

10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x and 10x will not pay a placement fee.

Please be aware of recruitment scams impersonating 10x Genomics. All recruiting communication will come from email addresses @. We also want to encourage you to apply to 10x Genomics positions directly on our careers site or from reputable third party sites such as LinkedIn or Indeed. We will never request payment or sensitive personal information during the recruiting process.