Sr. Scientist, Delivery Sciences
Cambridge, MA - USA
Job Summary
The Role:
We are seeking an accomplished Scientist to lead the development of targeted lipid nanoparticle (LNP) formulations within our fast-paced cross-functional R&D this role you will advance the science of LNP self-assembly engineer delivery systems for small- and large-molecule payloads beyond the liver and leverage state-of-the-art analytical techniques to establish structurefunction relationships that drive biological performance. You will also integrate high-throughput formulation laboratory automation and AI/ML-enabled approaches to accelerate LNP discovery and support data-driven decision-making across multidisciplinary research programs.
Heres What Youll Do
Drive research programs on targeted extra-hepatic LNP deliveryfrom hypothesis generation through in-vitro / in-vivo evaluation
Develop and optimize LNP self-assembly processes; refine composition payload loading and surface modifications for tissue and cell-type specificity
Advance LNP formulation discovery by leveraging high-throughput formulation automation and AI/ML-enabled data analysis to accelerate innovation optimize formulations and drive data-informed decision-making across multidisciplinary teams
Independently Design and execute experiments; analyze interpret and clearly communicate data to multidisciplinary project teams and leadership
Implement and innovate advanced physicochemical and biophysical characterization methods (e.g. DLS CryoEM SAXS ITC NMR nFCM etc) to elucidate structurefunction relationships
Maintain rigorous electronic laboratory notebooks SOPs and study documentation consistent with company expectations
Provide scientific leadership and mentorship to research associates while partnering with cross-functional teams and external collaborators to prioritize activities solve technical challenges and ensure the timely achievement of project objectives and key milestones.
Heres What Youll Need (Basic Qualifications)
Ph.D. in Pharmaceutical Sciences Chemistry Chemical Engineering Materials Science or a related discipline with 2 years of experience.
Deep expertise in lipid nanoparticle (LNP) design formulation and physicochemical characterization with experience advancing targeted or extra-hepatic delivery platforms preferred.
Demonstrated experience implementing high-throughput formulation workflows laboratory automation and computational or AI/ML-enabled data analysis to accelerate discovery and support data-driven decision-making.
Proven leadership experience mentoring scientists and research associates with a track record of driving cross-functional collaboration and delivering research objectives in a fast-paced environment.
Proficiency with a broad suite of analytical techniques for nanoparticle size morphology composition and stability assessment
This position is site-based requiring you to be at Modernas site full-time. This position is not eligible for remote work
Heres What Youll Bring to the Table (Preferred Qualifications)
Demonstrated ability to plan and manage multiple projects in a highly collaborative fast-paced setting
Clear concise scientific communicationwritten and verbalwith a track record of peer-reviewed publications and/or patents
Commitment to inclusive teamwork continuous learning and high scientific rigor
Pay & Benefits
At Moderna we believe that when you feel your best you can do your best work. Thats why our benefits and well-being resources are designed to support youat work at home and everywhere in between.
- Competitive healthcare plus voluntary benefit programs to support your unique needs
- A holistic approach to well-being with access to fitness mindfulness and mental health support
- Family planning benefits including fertility adoption and surrogacy support
- Generous paid time off including vacation volunteer days sabbatical global recharge days and a discretionary year-end shutdown
- Savings and investments to help you plan for the future
- Location-specific perks and extras
The salary range for this role is $130800.00 - $209400.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individuals position within the salary range will be based on several factors including but not limited to specific competencies relevant education qualifications certifications experience skills performance and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus other incentive compensation or equity award subject to company plan eligibility criteria and individual performance.
About Moderna
Since our founding in 2010 we have aspired to build the leading mRNA technology platform the infrastructure to reimagine how medicines are created and delivered and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.
By living our mission values and mindsets every day our people are the driving force behind our scientific progress and our culture. Together we are creating a culture of belonging and building an organization that cares deeply for our patients our employees the environment and our communities.
We are proud to have been recognized as a Science Magazine Top Biopharma Employer a Fast Company Best Workplace for Innovators and a Great Place to Work in the U.S.
If you want to make a difference and join a team that is changing the future of medicine we invite you to visit to learn more about our current opportunities.
Our Working Model
As we build our company we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation teamwork and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn contribute and make a meaningful impact.
Moderna is a smoke-free alcohol-free and drug-free work environment.
Equal Opportunities
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry or citizenship ethnicity disability military or protected veteran status genetic information sexual orientation marital or familial status or any other personal characteristic protected under applicable is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day please apply!
Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories consistent with legal requirements.
Accommodations
Were focused on attracting retaining developing and advancing our employees. By cultivating a workplace that values diverse experiences backgrounds and ideas we create an environment where every employee can contribute their best.
Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at .
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Required Experience:
Senior IC
About Company
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