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Sr. Scientific Lab Operations Manager


Job Location:

San Diego, CA - USA

Monthly Salary: Not provided by the employer
Posted: 15 August 2026 (21 days ago)
Application Deadline: 12 November 2026
Vacancies: 1 Vacancy

Job Summary

At RayzeBio every day is an opportunity to ignite meaningful change. As a wholly-owned subsidiary of Bristol Myers Squibb RayzeBio blends the nimble pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer. Here youll join a multidisciplinary team where your ideas are valued your expertise is amplified and collaboration is at the heart of everything we do. From day one expect to make an immediate impacton our science on our teams and most importantly on patients. Learn more about RayzeBio: a Bristol Myers Squibb company is a dynamic biotechnology company headquartered in San Diego CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team RayzeBio aims to be the global leader in radiopharmaceuticals

Job Description

We are seeking a highly motivated scientifically trained Senior Scientific Lab Operations Manager to lead laboratory operations and partner strategically with the R&D team. This role combines scientific expertise with operational excellence to optimize inventory study workflows instrument utilization and research productivity. The ideal candidate has experience in molecular biology cell biology or chemistry lab operations; understands common research instrumentation; and proactively improves laboratory efficiency while maintaining a safe compliant environment.

The ideal candidate combines deep scientific experience with operational leadership and serves as a trusted partner to Discovery scientists. This individual is expected to proactively identify opportunities to improve laboratory infrastructure operational efficiency and scientific productivity while ensuring a safe compliant and collaborative research environment.

Job Responsibilities

Essential duties and responsibilities include the following; other duties may be assigned.

  • Partner with Discovery leadership to anticipate laboratory needs and develop scalable operational plans aligned with current and future research priorities.
  • Establish standardized procedures and workflows that improve efficiency quality reproducibility and compliance.
  • Manage laboratory budgets capital planning forecasting service contracts and CAPEX/non-CAPEX purchases in alignment with scientific needs.
  • Lead laboratory infrastructure projects including expansions renovations equipment installations relocations and space planning.
  • Drive continuous improvement by identifying operational bottlenecks implementing sustainable solutions and monitoring relevant laboratory KPIs.
  • Collaborate with EHS Facilities IT Procurement Scientific Leadership and the RSO to maintain safe compliant and uninterrupted laboratory operations.
  • Serve as the primary point of contact for laboratory operational and technical issues including equipment malfunctions and service coordination.
  • Oversee equipment lifecycle management including selection installation calibration preventive maintenance repairs vendor management and record retention.
  • Manage laboratory systems and platforms for inventory consumable ordering training purchase orders and LIMS-related workflows.
  • Anticipate study needs and maintain appropriate inventory equipment readiness and laboratory capacity to support daily research activities.
  • Coordinate onboarding for new scientists including laboratory access training workspace preparation and equipment readiness.
  • Evaluate emerging laboratory technologies and recommend tools that improve scientific productivity and operational efficiency.
  • Support audit and inspection readiness including required documentation and laboratory records.
  • Organize cross-functional laboratory meetings track actions and ensure timely follow-up.
  • Manage refrigerators freezers tissue culture equipment cleaning schedules and decontamination of BSCs and incubators.
  • Coordinate radioactive waste pickup and other hot-lab operational activities with the RSO.

Education and Experience

  • BS in Life Sciences Molecular Biology Cell Biology Chemistry Biochemistry or a related scientific discipline with a minimum of 12 years of experience as a scientist including laboratory operations experience; OR an MS in a related discipline with a minimum of 10 years of scientific and laboratory operations experience.
  • Demonstrated experience supporting research laboratories in a biotechnology or pharmaceutical R&D environment.
  • Experience leading laboratory operations laboratory infrastructure scientific equipment management and laboratory process optimization.
  • Demonstrated knowledge of laboratory operations and commonly used biology laboratory equipment.
  • Knowledge of laboratory safety protocols including Cal/OSHA requirements and hazardous waste management.
  • Experience managing laboratory budgets capital equipment purchases (CAPEX) vendor relationships and service contracts.
  • Experience implementing laboratory systems digital tools or LIMS to improve operational efficiency is preferred.
  • Experience supporting cross-functional Discovery research teams in a fast-paced environment.

Skills

  • Strong scientific background with the ability to understand Discovery research workflows and anticipate laboratory needs.
  • Excellent project management and organizational skills with demonstrated ability to manage multiple complex initiatives simultaneously.
  • Strong financial acumen including budget planning forecasting and capital equipment management.
  • Experience influencing stakeholders across multiple scientific functions without direct authority.
  • Demonstrated ability to identify operational challenges and implement scalable solutions.
  • Experience with laboratory information management systems (LIMS) electronic inventory systems and digital laboratory platforms.
  • Excellent leadership collaboration and customer-service mindset focused on enabling scientific productivity.
  • Capability with Claude or other AI platforms to enhance operational efficiency.
  • Highly organized and detail-oriented with strong interpersonal skills accountability and a service mindset.
  • Ability to manage multiple priorities and responsibilities in a fast-paced environment
  • Strong communication skills and the ability to balance competing stakeholder needs
  • Strong understanding of scientific concepts and terminology
  • Must be able to follow instructions and maintain a safe work environment
  • Uses AI tools to enhance individual productivity and quality of work

Physical Demands

While performing the duties of this job the employee is regularly required to sit reach with hands and arms and talk or hear. The employee must occasionally lift and/or move up to 20 pounds. Specific vision abilities include close and distance vision. This position requires work in a laboratory environment. Protective clothing gloves and safety glasses are required while working with radioactive materials.

WorkEnvironmentThe work environment is usually moderately noisy.

If you come across a role that intrigues you but doesnt perfectly line up with your resume we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview:

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job such as required skills where the job is performed the employees work schedule job-related knowledge and experience. Final individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits please visit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

  • Health Coverage: Medical pharmacy dental and vision care.

  • Wellbeing Support: Programs such as BMS Well-Being Account BMS Living Life Better and Employee Assistance Programs (EAP).

  • Financial Well-being and Protection: 401(k) plan short- and long-term disability life insurance accident insurance supplemental health insurance business travel protection personal liability protection identity theft benefit legal support and survivor support.

Work-life benefits include:

Paid Time Off

  • US Exempt Employees: flexible time off (unlimited with manager approval 11 paid national holidays (not applicable to employees in Phoenix AZ Puerto Rico or Rayzebio employees)

  • Phoenix AZ Puerto Rico and Rayzebio Exempt Non-Exempt Hourly Employees: 160 hours annual paid vacation for new hires with manager approval 11 national holidays and 3 optional holidays

Based on eligibility* additional time off for employees may include unlimited paid sick time up to 2 paid volunteer days per year summer hours flexibility leaves of absence for medical personal parental caregiver bereavement and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

*Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours depending on the nature of their work and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors leased workers and other service providers are not eligible to participate in the program.

RayzeBio and Bristol Myers Squibb

RayzeBio was acquired by Bristol Myers Squibb (BMS) in 2024 and is a wholly-owned subsidiary of BMS; however RayzeBio will continue to operate as a standalone organization.

Supporting People with Disabilities

BMS and RayzeBio are dedicated to ensuring that people with disabilities can excel through a transparent recruitment process reasonable workplaceaccommodations/adjustmentsand ongoing support in their roles. Applicants can request a reasonable workplaceaccommodation/adjustmentprior to accepting a job offer. If you require reasonableaccommodations/adjustmentsin completing this application or in any part of the recruitment process direct your inquiries to. Visit access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS and RayzeBio will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position please visit this page for important additional information: Protection

We will never request payments financial information or social security numbers during our application or recruitment process. Learn more about protecting yourself at data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If you believe that the job posting is missing information required by local law or incorrect in any way please contact BMS at . Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response.

R: Sr. Scientific Lab Operations Manager

Required Experience:

Manager


About Company

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Bristol-Myers Squibb is a global biopharmaceutical company focused on discovering, developing and delivering innovative medicines for patients with serious diseases. Our medicines are helping millions of patients around the world in disease areas such as oncology, cardiovascular, immu ... View more

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