Sr Director, Disease Area Lead GKD Disease Strategy Team

Job Description

General Summary:

The Senior Director BSMO (Biopharmaceutical Sciences & Manufacturing Operations) GKD (Genetic Kidney Disease) Disease Area Lead represents BSMO at the GKD Disease Strategy Team (DST). The incumbent will provide strategic and operational leadership for all BSMO activities supporting programs within the GKD DST. This role is accountable for driving an integrated BSMO program strategy alignment and execution across Pharmaceutical Sciences CMTO Quality Supply Chain Regulatory Finance and other relevant functions to support development launch and lifecycle management of disease area products.

As a core member of the GKD DST this leader will partner crossfunctionally to translate disease strategy into executable technical and operational plans that enable reliable compliant delivery of medicines for patients with serious metabolic disease. By sitting on the GKD DST this role ensures alignment of BSMO priorities and resources with the broader disease area strategy and ensures that both BSMO has appropriate visibility to the disease area on-going developments and that the DST has a clear understanding of BSMO activities and capabilities. This role reports to the Vice President Disease Team Integration with a dottedline relationship to the Vice President Disease Area Executive GKD.

Key Duties and Responsibilities:

• Lead the development and execution of the BSMO program strategy for GKD programs aligned with disease clinical & commercial strategies.
• Serve as the BSMO representative on the GKD Disease Strategy Team (DST) supporting governance planning and risk discussions.
• Provide integrated leadership across Pharmaceutical Sciences CMTO Quality Supply Chain and external partners to ensure program readiness.
• Partners cross-functionally within BSMO to ensure integration of plans to develop and commercialize disease area products ensuring regulatory compliance.
• Support CMC regulatory strategy and submissions in partnership with Regulatory including health authority interactions as needed.
• Lead crossfunctional BSMO teams to deliver against program milestones in a matrixed environment which requires having a robust understanding of the role of each BSMO function.
• Build effective partnerships with internal stakeholders both within BSMO and more broadly across Vertex.
• Identify and manage programlevel technical operational and supply risks ensuring appropriate escalation and mitigation planning.
• Own BSMO program budgets forecasts and resource plans aligning with functional and DST priorities.
• Track and communicate program status KPIs and risks to BSMO and GKD leadership.

Knowledge and Skills:

• Advanced knowledge of manufacturing development and/or supply.
• Capability to build cross-functional alignment including R&D Pharmaceutical Sciences Regulatory Finance Commercial and Manufacturing partners.
• Excellent verbal written and presentation skills.
• Demonstrated expertise in critical thinking influence negotiation problem solving strategic thinking and leadership in a matrix environment.
• Demonstrated strong leadership capability.
• Demonstrated ability to influence areas not under direct control to achieve objectives and effectively communicate challenging goals and objectives.

Education and Experience:

• Advanced degree in Chemistry Chemical Engineering Pharmaceutical Sciences or a related discipline; PhD and/or MBA preferred.
• 12 years of experience or equivalent in pharmaceutical development manufacturing and supply chain.
• Demonstrated experience leading crossfunctional program teams.

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this Hybrid-Eligible role you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at