Sr. Associate Scientist, Pharmacokinetic (PK) Bioanalysis

At Gilead were creating a healthier world for all people. For more than 35 years weve tackled diseases such as HIV viral hepatitis COVID-19 and cancer working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the worlds biggest health challenges and our mission requires collaboration determination and a relentless drive to make a difference.

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Job Description

We are seeking a highly motivated Senior Associate Scientist Pharmacokinetic (PK) Bioanalysisto join the Discovery Science & Technology (DST) group and contribute to drug discovery efforts across multiple therapeutic areas including oncology inflammation and virology. The Discovery Science & Technology group is dedicated to identifying and advancing best-in-class and first-in-class therapeutic candidates through the application of state-of-the-art in vitro pharmacology technologies.

Our multidisciplinary scientific team leverages expertise in high-throughput screening assay development lab automation analytical chemistry biochemistry cell biology and biophysics to enable critical drug discovery decisions and facilitate the advancement of innovative medicines.

The successful candidate will be versatile in adapting in vitro pharmacology approaches to support target validation lead discovery and candidate advancement and the development and execution of biological biochemical cell-based and bioanalytical assays. Working within multidisciplinary teams this individual will generate high-quality data solve complex scientific challenges and help drive the discovery of transformative therapies for patients.

As a Senior Associate Scientist Pharmacokinetic (PK) Bioanalysis at Gilead you will ...

Key Responsibilities

• Design develop optimize and execute biological biochemical biophysical cell-based and bioanalytical assays to support drug discovery programs across multiple therapeutic areas.

• Contribute to target validation lead identification lead optimization and candidate selection activities by generating high-quality experimental data and scientific insights.

• Apply a diverse range of in vitro pharmacology technologies including high-throughput screening profiling mechanistic characterization and functional assay platforms to address critical research questions.

• Independently design and execute experiments analyze and interpret data and communicate findings to multidisciplinary project teams.

• Develop optimize and execute ligand-binding assays and related bioanalytical methods to support pharmacokinetic and translational research activities.

• Support in vivo pharmacokinetic studies through biological sample analysis data review and interpretation.

• Manage experimental challenges and implement creative solutions to improve assay performance robustness reproducibility and throughput.

• Collaborate closely with scientists across biology biochemistry biophysics analytical chemistry automation DMPK and data science to advance discovery programs.

• Contribute to the evaluation implementation and development of innovative technologies methodologies and workflows that enhance scientific impact and operational efficiency.

• Support automated and high-throughput workflows through assay optimization miniaturization and integration with laboratory automation platforms.

• Maintain accurate and organized experimental records and prepare technical reports presentations and scientific summaries.

• Present scientific findings and recommendations to project teams and departmental meetings.

• Contribute to a culture of scientific excellence innovation collaboration and continuous learning.

Basic Qualifications

• Bachelors degree in Biology Biochemistry Pharmacology Molecular Biology Bioengineering Pharmaceutical Sciences or a related scientific discipline with 5 years of relevant industry experience OR

• Masters degree in Biology Biochemistry Pharmacology Molecular Biology Bioengineering Pharmaceutical Sciences or a related scientific discipline with 3 years of relevant industry experience.

Preferred Qualifications

• Industry experience supporting drug discovery translational research assay development screening sciences pharmacology bioanalysis or a related scientific discipline.

• Demonstrated experience developing optimizing and executing biological biochemical cell-based and/or bioanalytical assays.

• Experience supporting in vivo pharmacokinetic (PK) studies through sample analysis data generation and interpretation.

• Proven ability to independently design experiments analyze complex datasets interpret results and recommend next steps.

• Experience working in multidisciplinary research environments and collaborating effectively across scientific functions.

• Demonstrated ability to manage multiple priorities in a dynamic research setting while maintaining high scientific standards.

• Track record of identifying technical challenges and implementing effective scientific solutions.

• Strong understanding of assay development principles experimental design and data analysis.

• Hands-on experience with one or more laboratory disciplines including cell biology biochemistry enzymology pharmacology protein sciences biophysics screening sciences and/or bioanalysis.

• Experience developing optimizing and troubleshooting ligand-binding assays (LBA) such as ELISA MSD Gyrolab AlphaLISA or related technologies.

• Experience analyzing biological samples including serum plasma and other matrices to support pharmacology and pharmacokinetic studies.

• Working knowledge of pharmacokinetic principles and interpretation of bioanalytical data.

• Experience with laboratory automation and software commonly used in drug discovery and bioanalytical research.

• Demonstrated ability to troubleshoot and improve assay performance robustness reproducibility and throughput.

• Strong analytical and problem-solving skills with the ability to translate complex experimental data into actionable scientific insights.

• Excellent written verbal and presentation skills.

• Ability to work independently while contributing effectively within cross-functional teams.

• Experience with high-throughput screening (HTS) compound profiling assay miniaturization or automated laboratory workflows.

• Experience supporting PK PD biomarker or bioanalytical studies for biologics and other large-molecule therapeutic modalities.

• Familiarity with biologics peptides antibody-drug conjugates (ADCs) and other large-molecule therapeutic modalities.

• Understanding of PK/PD principles and their application in discovery and early development.

• Experience with analytical technologies such as LC-MS/MS or other quantitative characterization platforms

The salary range for this position is: $126820.00 - $164120.00. Gilead considers a variety of factors when determining base compensation including experience qualifications and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus discretionary stock-based long-term incentives (eligibility may vary based on role) paid time off and a benefits package. Benefits include company-sponsored medical dental vision and life insurance plans*.

For additional benefits information visit:

Eligible employees may participate in benefit plans subject to the terms and conditions of the applicable plans.

Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment and is dedicated to fostering an inclusive work environment comprised of diverse perspectives backgrounds and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race color religion national origin sex age sexual orientation physical or mental disabilitygenetic information or characteristic gender identity and expression veteran status or other non-job related characteristics or other prohibited grounds specified in applicable federal state and local order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973 the Vietnam Era Veterans Readjustment Act of 1974 and Title I of the Americans with Disabilities Act of 1990 applicants who require accommodation in the job application process may contact for assistance.

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