SeniorClinical Trial Manager (CTM)

Join Us in Tackling Autoimmune Disease at Its Root

At Vor we believe science can do more than manage symptoms. It can change the course of disease. By advancing telitacicept a first- and potentially best-in-class dual BAFF/APRIL inhibitor we are silencing upstream survival signals and stopping downstream autoimmune cascades. Together we are addressing disease at its root cause and rewriting what is possible for patients worldwide.

When you join Vor youre not just working on a medicine. Youre part of a mission to redefine the future of autoimmune care.

Why Work at Vor

Impact: Contribute directly to a medicine with best-in-disease Phase 3 results in myasthenia gravis and expansion into multiple autoimmune diseases.

Growth: Be part of a rapidly scaling company with opportunities to grow your career in science clinical development commercial strategy and beyond.

Innovation: Work on a platform with potential beyond one indication a therapy that has already shown consistent results across lupus IgA nephropathy and Sjögrens syndrome.

Belonging: Join a culture where every voice is heard and where our shared mission unites us across functions and geographies.

Who we are looking for:

VorBiopharma is seekingaClinical Trial Manager/Sr. Clinical Trial Managerwhowill be responsible forleadingall aspects of clinical trial management from study start through study closure.

Key areas ofresponsibilities:

• Manage all clinical aspects ofa clinical trialand ensures trial executionin compliance with ICH/GCP guidelines/regulations and applicable SOPs
• Leadand collaborateeffectivelywithcross-functionalteams tooversee the setupexecutionandmanagementofVorBiopharmacomplexclinical trialsaccordingto plan and in the highest quality standards
• Canmulti-task in a fast-paced environment with changing prioritiesand maintainaccurate forecastsclinical trial budgetsand timelines
• Assist in development and management of study budget and maintains it within financial goals; reviews and approves clinical invoices against approved budget
• Useoperational and therapeutic expertise to optimize trialsetup implementationandexecution
• Proactivelyanticipate/identifystudy risks andissues determine escalation pathway anddevelop and implementssolutions
• Conduct project risk analysis and develops risk mitigation strategies for a variety of complex problemstomaintain study deliverables
• Provide technical expertiseto overseethedevelopment of clinical documents (protocol informed consent form CRF monitoring plans regulatory submission documents clinical study report investigator brochures etc.
• Provideclinical operationsexpertise and strategic leadership in the evaluationselectionand management ofCROsand other external vendors to ensure successful clinical trial implementation and executionofVorBiopharma clinical trialsandensure that performance expectations are met
• Provide expertise in the identification engagement and selection of key trial centers/PIsas well asdevelop relationships with investigators and site staff
• Ensure audit-ready condition of clinical trial documentationand supportinspection readiness activities
• Participatein the planning of quality assurance activities and coordinate resolution of audit findingswhich includes management through resolution (CAPA) of any site or study level issues deviations etc.
• Actively provide direction and oversight and foster effective relationships with vendors investigatorsconsultantsand colleagues
• Participate in the selection training and evaluation of study personnel (contract and internal) to ensure the efficient operation of the function
• Manage and mentor clinical team members as needed

Qualifications:

• BA or BSin ascientific life scienceor health-relateddiscipline;advanceddegree preferred
• CTM:Minimum of 5to 7years of experience in clinical researchwith 1-2 years managing trials in thebiotech/pharmaindustryand/or prior CRO experience
• Sr. CTM:Minimum of7yearsofexperience in clinical researchwith at least 3-5 years managing trials in thebiotech/pharmaindustryand/or prior CRO experience
• Experience in setup execution and oversight/operational management of autoimmune trial experience - Sjogrens or Myasthenia Gravis preferred
• Excellent communication writingand presentationskills withstrong problem-solving abilityand attentionto detail
• Strong initiative and a can-do attitude excellent organizational skills ability to prioritizedeliverables/tasks tomeet deadlinesproven effectiveness in afast-moving and growing biotechenvironment
• Solidworking knowledge in Good Clinical Practices and ICH Guidelinesand the application to the conduct of clinical trials
• Proficient in MS Office Suiteand understandingClinicalTrialManagementSystemeTMF andEDCsystems is required
• Ability/willingness to travelboth domestically and internationally as required

The salary range for the Clinical Trial Manager is expected to be between $140000 and $155000 per year. Individual pay may vary based on multiple factors including but not limited to relevant job-related skills experience education or training market factors and work location.

The salary range for the Senior Clinical Trial Manager is expected to be between $175000 and $195000 per year. Individual pay may vary based on multiple factors including but not limited to relevant job-related skills experience education or training market factors and work location.

At Vor we support our team with robust benefits including comprehensive health coverage flexible paid time off generous parental leave and a competitive 401(k). From education assistance to wellness resources and financial security we invest in your well-being so you can thrive at work and beyond.

As an equal opportunity employer we at Vor Bio know that diversity inspires innovation inclusiveness and creativity. We invite you to come as you are. All applicants will be considered for employment agnostic to race age color religion sex sexual orientation gender identity national origin veteran or disability status.

Please visit our website at for more information.