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Senior Software Test Engineer

Illumina


Job Location:

San Diego, CA - USA

Monthly Salary: $ 107700 - 161500
Posted: 22 August 2026 (2 days ago)
Application Deadline: 19 November 2026
Vacancies: 1 Vacancy

Job Summary

What if the work you did every day could impact the lives of people you know Or all of humanity

At Illumina we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person in every role has the opportunity to make a difference. Surrounded by extraordinary people inspiring leaders and world changing projects you will do more and become more than you ever thought possible.

The Senior Software Test Engineer will serve as the test owner for assigned software subsystems within Illuminas complex DNA sequencing instruments. This role is within our Instrument Software Organization on the Hardware Frameworks team which develops shared software components used to integrate instrument applications with firmware and physical hardware.

The candidate will shape test strategy throughout the development process working with cross-functional partners to identify risks improve testability and define appropriate verification coverage. Responsibilities also include hands-on testing on sequencing instruments ownership of subsystem verification and investigation of complex failures spanning software firmware and hardware.

This is primarily a software testing and systems-integration role. Test automation coding skill and test-tool development are valuable but are not main responsibilities and are not required.

Key Responsibilities
  • Serve as the test owner for assigned software features or subsystems.

  • Participate in requirements design and planning activities to identify quality risks improve testability and influence the overall test strategy.

  • Define risk-based verification coverage across functional integration system and regression testing.

  • Develop test plans test cases and test procedures from product system and software requirements.

  • Perform hands-on testing and feature integration on DNA sequencing instruments in a laboratory environment.

  • Work closely with cross-functional stakeholders to test workflows and address quality risks and release-ready concerns.

  • Validate workflows spanning user interfaces backend services hardware abstraction software firmware simulators and physical instrument hardware.

  • Perform root cause analysis in collaboration with software firmware hardware systems integration and quality teams.

  • Provide technical guidance to supporting engineers and contribute to improvements in team testing practices.

  • Work within established software-development quality and requirements-management processes for regulated products.

Qualifications
  • Five or more years of professional experience in software quality engineering instrument software testing embedded-system testing or a related discipline.

  • Experience with functional integration system and regression testing.

  • Experience independently developing test strategies test plans and detailed test cases from technical requirements.

  • Experience owning feature- or subsystem-level verification including requirements traceability and verification evidence.

  • Strong troubleshooting and analytical skills including the ability to isolate failures across technical boundaries.

  • Familiarity with defect tracking and requirements management platforms such as Jira and Jama.

  • Ability to work regularly with physical instruments in a laboratory environment.

  • Strong written and verbal communication skills and the ability to collaborate across technical disciplines.

Nice to Have
  • Experience using AI-assisted engineering tools such as Cursor or GitHub Copilot to support test design troubleshooting documentation or workflow improvement;

  • Familiarity with Linux environments and command-line tools.

  • Familiarity with embedded systems communication protocols or hardware diagnostic equipment.

  • Familiarity working in a regulated environment (e.g. medical devices).

Education
  • Bachelors degree in Computer Science Software Engineering Electrical Engineering Biomedical Engineering or a related technical field or equivalent practical experience.

Work Arrangement

This is a hybrid position requiring on-site work at least three days per week. Additional on-site presence may be required based on laboratory activities and business needs.

#LI-HYBRID

The estimated base salary range for the Senior Software Test Engineer role based in the United States of America is: $107700 - $161500. Should the level or location of the role change during the hiring process the applicable base pay range may be updated accordingly. The range reflects longterm growth in the role; therefore most candidates are hired between the minimum and middle of the range. Placement depends on experience skills location and internal equity. Additionally all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work including access to genomics sequencing family planning health/dental/vision retirement benefits and paid time off.

We are a company deeply rooted in belonging promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation Illumina has always prioritized openness collaboration and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay regardless of gender ethnicity or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences increase cultural awareness and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex race creed color gender religion marital status domestic partner status age national origin or ancestry physical or mental disability medical condition sexual orientation pregnancy military or veteran status citizenship status and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local state and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local state and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process please contact To learn more visit: The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.

Required Experience:

Senior IC