Senior Scientist I, Drug Delivery Sciences and Engineering

We are seeking a highly motivated Senior Scientist I to join the Drug Delivery Sciences and Engineering team in Irvine this laboratory-based role you will independently design and execute studies to develop and characterize innovative drug delivery systems for small molecules and biologic modalities including peptides and proteins. You will apply expertise in chemistry formulation polymer and protein science and pharmaceutical characterization while partnering across discovery and development functions to advance programs. The ideal candidate combines strong scientific judgment hands-on experimental capability and clear and concise communication with a collaborative results-oriented approach.

Key Responsibilities:

• Independently design execute analyze and document laboratory studies supporting novel drug delivery systems and enabling formulations.
• Develop and optimize delivery approaches for small molecules and biologics including proteins and peptides with emphasis on sustained controlled or targeted delivery.
• Apply principles of formulation protein polymer and colloid science to address stability compatibility manufacturability and performance challenges.
• Characterize formulations and delivery systems using relevant analytical and biophysical methods which may include HPLC ELISA DSC FTIR GPC/SEC MALS/DLS rheology spectroscopy particle-size analysis and in vitro release testing.
• Interpret complex data identify technical risks develop hypotheses and recommend practical experimental strategies and mitigation plans.
• Represent Drug Delivery Sciences and Engineering on cross-functional project teams and clearly communicate study plans results risks and recommendations.
• Maintain complete timely and compliant experimental records and prepare technical reports presentations development documentation publications and invention disclosures as appropriate.
• Monitor advances in drug delivery technologies and identify opportunities to introduce new capabilities platforms or more efficient workflows.
• Collaborate with internal partners and external laboratories or vendors to execute studies transfer methods and meet project objectives.
• Contribute to a safe inclusive and high-performing laboratory environment and provide technical guidance or training to colleagues interns or junior scientists as needed.

Qualifications :

Required:

• Ph.D. in chemistry biochemistry chemical engineering pharmaceutical sciences or a related discipline with 04 years of relevant experience; M.S. with at least 8 years of relevant experience or Bachelor Degree with 10 years of experience.
• Strong scientific foundation in chemistry drug delivery formulation science protein science polymer science biomaterials or a closely related field.
• Demonstrated ability to independently design experiments troubleshoot technical challenges critically analyze data and draw scientifically sound conclusions.
• Hands-on experience with pharmaceutical formulation and relevant analytical or biophysical characterization methods.
• Strong written and verbal communication skills including the ability to present complex scientific information clearly to multidisciplinary audiences.
• Demonstrated effectiveness in cross-functional collaboration and the ability to build productive working relationships.
• Ability to manage multiple priorities adapt to changing program needs and deliver high-quality results in a fast-paced research environment.

Preferred Qualifications:

• Experience developing sustained-release controlled-release targeted polymer-based particulate conjugate hydrogel or other advanced delivery systems.
• Experience with biologic modalities such as proteins peptides or nucleic acids.
• Experience with bioconjugation chemistry and synthetic methods.
• Knowledge of formulation stability degradation mechanisms drugexcipient interactions and in vitro release or performance testing.
• Experience using Design of Experiments multivariate analysis or related statistical approaches for formulation or process optimization.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at  the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors  including  geographic location and we may ultimately  pay more or less than the posted range. This range may be  modified in the future. 

• We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.

• This job is eligible to  participate in our short-term incentive programs.  

Note: No amount of pay is  considered to be wages or compensation until such amount is earned  vested  and determinable. The amount and availability of  any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a   particular employee  remains in the Companys sole and absolute discretion unless and until paid and may be  modified at the Companys sole and absolute discretion  consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more visit  & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:

Work :

No

Employment Type :

Full-time