Senior Scientist I BDL Modeling

The Senior Scientist I will be part of a centralized modeling team supporting the development and implementation of a broad range of models across early- and late-stage bioprocess development for diverse biologic modalities including monoclonal antibodies antibody-drug conjugates bispecifics and gene therapies. Working collaboratively across functions the scientist will develop and apply innovative modeling and experimental approaches to address scientific and process development challenges including scale-up and technology transfer. The teams mission is to continually build next-generation modeling capabilities through deep integration with artificial intelligence (AI) tools delivering business impact with agility.

Responsibilities: 

• Independently conceptualize build and apply fit-for-purpose models for upstream cell culture and downstream purification processes across early- and late-stage bioprocess development.
• Translate scientific and business challenges into modeling strategies that deepen process understanding guide process optimization and support scale-up and technology transfer.
• Advance next-generation modeling capabilities through deep integration with AI tools to accelerate model development and implementation and deliver business impact with agility.
• Work closely with the Automation and Digitalization team to establish data workflows and integrated tools that enable efficient model building and implementation.
• Integrate multidisciplinary data and scientific fundamentals to assess model performance assumptions and limitations draw actionable conclusions and resolve key project challenges.
• Collaborate in an agile fast-paced matrix team spanning IT Data Science CMC and Development to align priorities adapt to evolving needs and deliver modeling solutions; provide scientific mentorship and technical guidance as appropriate.
• Communicate modeling approaches results limitations and recommendations clearly and efficiently to project teams and leadership to support timely informed decisions.
• Support model transfer and lifecycle management including implementation documentation maintenance updates and assessment of continued fitness for purpose in accordance with applicable corporate safety and GxP standards.
• Serve as a primary author of modeling-related technical and regulatory documents peer-reviewed publications and scientific presentations and contribute to patentable innovations as appropriate.
• Proactively evaluate relevant literature and emerging technologies identify innovative modeling opportunities aligned with the centralized teams strategy and incorporate advances into projects and broader modeling capabilities.

Qualifications :

• Bachelors degree or equivalent education and typically 10 years of experience Masters degree or equivalent education and typically 8 years of experience PhD degree or equivalent education and 0-2 years of experience.
• Education background in chemical engineering biomedical engineering biochemistry biochemical engineering or biotechnology is preferred.
• Experience in both upstream cell culture and downstream purification process development is preferred. Demonstrated expertise in computational fluid dynamics (CFD) modeling cell culture kinetics and metabolic flux balance modeling chromatography modeling and filtration theory and modeling is preferred.
• Familiarity with AI tool development and experience integrating AI tools into the bioprocess development ecosystem.
• Demonstrate excellent communication skills and specifically illustrate strong oral and written technical communications. Seamlessly present research outcomes to multifunctional teams
• Play a strong team player in a cross functional collaborative environment thriving for world class excellence and maintains strong working relationships with internal global and external collaborators.
• Demonstrated problem-solving skills and capability to overcome complex issues.
• Demonstrated success in coordinating and executing important projects to achieve business goals.
• Must have a results-oriented work ethic and a positive can-do attitude with a strong sense of urgency and self-motivated desire to achieve.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future. 
• We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs. 

Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of  any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more visit  & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:

Work :

No

Employment Type :

Full-time