Senior Research Associate
Job Location:
Boston, MA - USA
Hourly Salary:
$ 56 - 57
Posted:
15 October 2026 (Yesterday)
Application Deadline:
12 January 2027
Vacancies:
1 Vacancy
Job Summary
Senior Research Associate Next-Generation Sequencing (NGS) needs 35 years of bench experience falls dire
- End-to-End Library Prep: Lead RNA-seq bulk amplicon and highly specialized single-cell (scRNA-seq) and single-nucleus (snRNA-seq) sequencing workflows.
- Target Identification: Design and execute molecular and cell biology experiments to identify and validate novel drug targets.
- Assay Optimization: Support assay design optimization validation and complex data quality control (QC).
- Troubleshooting: Diagnose and resolve complex technical data anomalies to keep drug discovery projects moving forward.
- Collaborative Reporting: Translate complex experimental results into clear oral presentations and written documentation.
- Education & Experience: B.S. and/or M.S. in biological or biochemical sciences with 35 years of hands-on laboratory research experience.
- Molecular Biology Mastery: Proven expertise in nucleic acid extraction purification quantification qPCR and NGS library prep/QC.
- Advanced Sequencing Background: Deep understanding of NGS technologies and data QC (preferably Illumina) with direct experience in bulk RNA-seq and amplicon-seq.
- Single-Cell Expertise: Direct experience with scRNA-seq and snRNA-seq library preparation is required. You must be familiar with multiple platforms (e.g. 10X Genomics Chromium Illumina PIP-seq ScaleBio or Parse Biosciences).
- Operational Excellence: Experience documenting experiments in electronic notebook software alongside exceptional organizational and time-management skills.
Preferred Extras (A Plus But Not Required)
- Familiarity with CRISPR-based gene editing and high-throughput screening.
- Experience operating lab automation equipment (Mantis Integra systems liquid handlers SPTLabtech Firefly Tecan etc.).