Senior MrgAssociate Dir, Clinical Science
Job Location:
San Diego, CA - USA
Yearly Salary:
Posted:
Application Deadline:
Vacancies:
Job Summary
Job Title: Senior Manager/Associate Director Clinical Science
Location: San Diego or Remote U.S.
Job Type: Full-Time
Who We Are
Avenzo Therapeutics Inc. (Avenzo or Company) is a clinical-stage biotechnology company focused on developing next-generation oncology therapies for patients. The Company was co-founded in 2022 by Drs. Athena Countouriotis and Mohammad Hirmand (former CEO and CMO of Turning Point Therapeutics Inc. respectively). Our team is passionate about and committed to advancing a pipeline of potentially differentiated targeted oncology programs that make a difference in the lives of people with cancer. The Company is headquartered in San Diego California.
Position Summary
Reporting to the Executive Director Clinical Science the Senior Manager/Associate Director Clinical Sciencewill provide scientific and clinical support for the design conduct analysis and reporting of clinical trials. This role contributes hands-on clinical expertise across study teams while collaborating closely across the organization to ensure high-quality scientific execution.
Essential Job Functions and Responsibilities
- Serve as the Clinical Science representative on cross-functional study teams providing scientific and clinical input to support study planning execution data review and study-related decision-making
- Contribute to the design and development of clinical studies including protocol development feasibility assessments study-related documents and clinical sections of regulatory submissions (e.g. INDs Investigators Brochures DSURs regulatory responses and case report forms)
- Partner with Clinical Operations Data Management Biostatistics Pharmacovigilance Regulatory Affairs and external vendors to support study execution protocol compliance subject safety and overall trial oversight
- Conduct ongoing clinical review of safety and efficacy data including data trend analysis signal identification assessment of data quality and completeness and communication of observations and recommendations to study teams
- Support safety monitoring activities through participation in safety review meetings Data Monitoring Committees review of safety narratives and safety-related documents and collaboration with Medical Monitoring and Pharmacovigilance colleagues
- Develop and review study training materials and support investigator meetings site initiation visits and other study-related training and communication activities
- Author and review clinical narratives support data review and study closeout activities and contribute to clinical study reports and other study deliverables
- Interact with investigators key opinion leaders and other internal and external subject matter experts to support study conduct and ensure alignment with scientific and regulatory requirements
- Contribute to study planning activities including review of CRO deliverables study budgets scopes of work and operational plans in collaboration with Clinical Operations and Clinical Outsourcing
- Support scientific communications through development of presentations abstracts posters publications and other internal and external materials
- Review scientific literature emerging clinical data and competitive intelligence to support study execution and clinical development activities
Preferred Qualifications
- Bachelors degree required advanced medical or life sciences or a related area degree preferred (e.g. MS Ph.D. MPH PharmD) with 6 years of experience in the life sciences industry or an equivalent combination of academic and industry experience
- Experience conducting clinical data listing reviews and demonstrating familiarity with standard clinical and regulatory references (e.g. CTCAE MedDRA)
- Working knowledge of principles and techniques of clinical data analysis and interpretation
- Experience reviewing and contributing to clinical study protocols and related documents
- Knowledge of GCP (Good Clinical Practice) ICH FDA EMA and other relevant guidelines and regulations
- Proven ability to collaborate within cross-functional teams
- Ability to understand and assimilate complex scientific and clinical information.
- Demonstrates initiative strong organizational skills and attention to detail.
- Proficiency in Microsoft Word Excel PowerPoint and Electronic Data Capture systems (e.g. RAVE) J-Review or similar data review tools
- Excellent communication and interpersonal skills with the ability to collaborate effectively with internal and external stakeholders
- Strong analytical and problem-solving abilities with a strategic mindset
- This position requires periodic/regular travel including up to 25% of work time which may include overnight travel
Physical Demands and Work Environment
Physical Demands:
- Constant or continuous use of a computer keyboard monitor and mouse to perform a variety of tasks
- Constant or frequent sitting standing or walking
- May lift and/or move objects of various weights
Work Environment:
- Remote: Home office; expected to travel to and work from the Companys headquarters in San Diego from time to time
- San Diego-based: On-site requirement (Monday through Thursday)
- Noise level in the work environment is usually moderate
- Fast-paced time sensitive environment with frequently changing priorities
- Handle multiple projects simultaneously
Reasonable accommodations may be provided to enable qualified individuals with disabilities to perform the essential functions of the position.
Salary Range
The salary range for this position for a Senior Manager is $182000 to $189000 per year. The salary range for this position for an Associate Director is $189000 to $196000 per year. The final pay offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and years of experience within the job and the industry education and skills and certifications.
Benefits
Provided they meet all eligibility requirements under the applicable plan documents employees (and their eligible dependents) will be eligible to enroll in group healthcare plans that offer medical dental vision and basic life and AD&D insurance. Additional benefit programs include short-term and long-term disability insurance flexible spending accounts health savings accounts and voluntary insurance programs including voluntary life AD&D accident and critical illness. Employees will also be able to enroll in the Companys 401(k) addition employees will accrue 10 hours of paid vacation time every month and accrue 1 hour of paid sick leave for every 30 hours worked. Employees also enjoy 17 paid holidays each calendar year including a winter closure subject to applicable Company policies. All benefits are subject to the terms and conditions of the applicable plan documents and Company policies which may be amended from time to time.
Other Compensation
The hired candidate will be eligible to receive an annual discretionary bonus and an equity award subject to the terms of the applicable employment agreement plan documents and Company policies.
The information above is intended to provide a general description of benefits and other compensation and is not a substitute for applicable plan documents or company policies.
Applications for this position are anticipated to close on September 30 2026 . For more information about this posting please contact.
Equal Employment Opportunity
Avenzo is committed to providing equal employment opportunities to all employees and applicants without regard to an individuals actual or perceived protected characteristic or characteristics or any combination of protected characteristics including race (including traits associated with race such as hair texture and protective hairstyles including braids locks and twists) ethnicity religion religious creed (including religious dress and grooming practices) color sex (including childbirth breast feeding and related medical conditions) gender gender identity or expression sexual orientation national origin ancestry citizenship status uniformed service member and veteran status marital status pregnancy age (40 and over) protected medical condition (including cancer and genetic conditions) genetic information disability (mental and physical) reproductive health decision-making medical leave or other types of protected leave (requesting or approved for leave under the Family and Medical Leave Act or the California Family Rights Act) the employee or their family members status as a victim of a qualifying act of violence political activity or affiliation use of cannabis off the job and away from the workplace association with an individual who has or is perceived to have a protected characteristic or characteristics or any combination of protected characteristics or any other protected status in accordance with all applicable federal state and local laws.
Notice to Search Firms/Third Party Agencies
Avenzo does not accept unsolicited resumes from recruiters employment agencies or search firms without a valid executed search agreement in place.
Required Experience:
Senior IC
