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Senior IT Project Leader


Job Location:

Cambridge, MA - USA

Monthly Salary: $ 128000 - 176000
Posted: 22 August 2026 (11 days ago)
Application Deadline: 19 November 2026
Vacancies: 1 Vacancy

Job Summary

Who We Are

Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation company creation and capital investment under one roof in a way that is largely without precedent. Our scientific founders entrepreneurial leaders and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.

Many of the companies Flagship has founded have addressed humanitys most urgent challenges: vaccinating billions of people against COVID-19 curing intractable diseases improving human health preempting illness and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNEs Change the World list an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Companys annual list of the Worlds Most Innovative Companies.

Position Overview

Flagship is seeking an experiencedSenior IT Project Leader to drive strategic technology initiatives across the enterprise. This role is ideal for a collaborative leader who thrives in ambiguity builds strong cross-functional partnerships and enjoys turning complex ideas into successful outcomes.

Reporting to the Senior Director of IT Performance the Project Leader will partner with technical teams business stakeholders and executive leadership to deliver initiatives aligned with Flagships strategy. Projects may span enterprise applications infrastructure cloud cybersecurity AI scientific systems and other strategic IT capabilities.

Rather than simply managing timelines the Project Leader serves as the connective tissue between business strategy and technology execution bringing people together aligning priorities removing obstacles and ensuring successful delivery.

What Youll Do

Lead Strategic Technology Initiatives

  • Lead complex cross-functional technology initiatives from planning through implementation and operational transition.
  • Partner with business and IT leaders to define project objectives scope success measures and delivery strategies.
  • Develop and manage integrated project plans schedules budgets resource forecasts and governance activities.
  • Ensure projects are delivered on time within budget and aligned with organizational priorities.

Drive Cross-Functional Leadership

  • Build trusted partnerships with business leaders technical teams and executive stakeholders.
  • Facilitate collaboration across multiple departments vendors and external partners.
  • Lead steering committee meetings executive updates and project governance forums.
  • Create alignment among diverse stakeholders while driving timely decision-making.

Manage Complexity and Risk

  • Anticipate and proactively manage project risks issues dependencies and scope changes.
  • Resolve delivery challenges by balancing business priorities technical constraints and organizational impacts.
  • Ensure project decisions are made by data risk assessments and strategic objectives.
  • Drive organizational readiness communications and change management activities to support successful adoption.

Advance Delivery Excellence

  • Champion consistent project management practices governance standards and delivery methodologies.
  • Develop executive-level reporting and portfolio insights that enable informed decision-making.
  • Identify opportunities to improve project delivery processes tools and operational effectiveness.
  • Capture lessons learned and promote continuous improvement across the IT organization.

Mentor and Influence

  • Serve as a trusted advisor to project teams and business partners on delivery strategy and execution.
  • Mentor project leaders and team members sharing best practices and fostering a culture of accountability and collaboration.
  • Contribute to the evolution of project leadership capabilities across the IT organization.

Required Qualifications

  • 8 years of experience leading increasingly complex technology projects and enterprise programs.
  • Demonstrated success delivering large-scale cross-functional technology initiatives in a matrixed organization.
  • Strong experience partnering with senior business and technology leaders.
  • Proven ability to influence without formal authority and build consensus across diverse stakeholder groups.
  • Experience managing project budgets timelines vendor relationships and resource planning.
  • Excellent communication facilitation presentation and organizational skills.
  • Strong analytical and problem-solving abilities with the ability to navigate ambiguity and competing priorities.

Preferred Qualifications

  • PMP or equivalent project management certification.
  • Experience with Agile Waterfall and hybrid delivery methodologies.
  • Experience with project management tools such as Jira Azure DevOps Smartsheet Microsoft Project or similar.
  • Experience leading technology initiatives involving cloud infrastructure cybersecurity enterprise applications AI digital workplace technologies or scientific computing.
  • Familiarity with organizational change management principles and change enablement strategies.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race color religion sex sexual orientation gender identity national origin disability protected veteran status or any other characteristic protected by law.

We recognize that great candidates often bring unique strengthswithout fulfilling every qualification. If you have some of the experience listed above but not all please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your backgroundand interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively FSP) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneerings internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP and FSP will not owe any referral or other fees with respect thereto.

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The salary range for this role is $128000 - $176000. Compensation for the role will depend on a number of factors including a candidates qualifications skills competencies and experience. Flagship Pioneering currently offers healthcare coverage annual incentive program retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneerings good faith estimate as of the date of publication and may be modified in the future.

Privacy Notice for Applicants:When you apply for a role at Flagship Pioneering or one of its portfolio companies we collect and use personal information you provide (such as your name contact details work history and application materials) to evaluate your application communicate with you and comply with legal obligations. Your application data is processed through Greenhouse our applicant tracking system and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know delete and opt out of the sharing of their personal information. If you are located in the EU or UK we process your data under GDPR and you have rights to access rectify and erase your data. To exercise your rights or for questions contact


Required Experience:

Senior IC


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We are Flagship Pioneering We are a biotechnology company that invents platforms and builds companies that change the world. Pioneering Partnerships…

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