Senior Global Medical Affairs Lead MASH

AstraZeneca is advancing a tailored approach to liver disease uniting science medical and commercial excellence to deliver durable outcomes reduce cardiometabolic risk and protect organs. Our pipeline is moving with purpose and includes next generation oral and injectable therapies that prioritises tolerability durability and quality of life. Are you ready to be at the forefront of medical innovation As the Senior Global Medical Affairs Leader for MASH youll play a pivotal role in shaping the future of liver disease. This is your chance to use your expertise to make a real impact on patients lives. Join us in our mission to transform the patient journey from prevention to diagnosis and beyond.

Accountabilities

In this dynamic role youll be responsible for providing medical leadership across the entire product lifecycle. Youll advise on Research & Development investment decisions lead pre-launch scientific efforts and accelerate evidence-based healthcare changes in the real world. Your networking and influencing skills will be key as you facilitate cross-functional collaboration and drive innovation. Are you ready to take on this challenge

Role Summary:

Reporting to the Medical Head of Weight Management the Senior GMAL is a highly experienced Medical Affairs leader with proven vision and impact. This individual develops and leads bold medical strategies for MASH within the Weight Management therapy area expertly guiding cross-functional and cross-regional teams to deliver and exceed ambitious goals. The Senior GMALs influence is enterprise-wideshaping global medical agendas through Global Medical Team Global Product Team and Disease Area Team leadership and deep partnership with Medical and Commercial functions in markets and regions worldwide.

This role demands a leader who champions innovative disruptive thinkingidentifies and shapes breakthrough opportunities reimagines market dynamics and accelerates high-impact evidence generation and medical change initiatives. The Senior GMAL navigates and transforms health systems leverages digital and advanced analytics drives stakeholder engagement and ensures AstraZenecas science leads externally and internally through world-class medical evidence and strategic partnerships.

Expectations of a Senior GMAL include:

• Strategy & Transformation:The Senior GMAL designs and leads the implementation of product and disease area strategies as well as ambitious practice change initiatives at a global level. This requires a deep understanding of healthcare system pathways regulatory landscapes market access and competitive dynamics. The Senior GMAL consistently delivers innovative disruptive solutions to shape markets challenges status quo thinking and uses digital proficiency to identify data-driven opportunities preparing for launch and life cycle management.

• Medical Evidence Leadership:Senior GMALs own the evidence generation strategydemonstrating advanced experience in clinical research interventional trials (Phases 24) and real-world evidence (RWE) programs. They shape and drive groundbreaking clinical trials registries and RWE studies aligned with brand access and practice-changing objectives. They guide the optimisation communication and strategic roll-out of data across scientific platforms ensuring AstraZeneca delivers differentiated evidence that supports the needs of regulatory payer and healthcare providers. Clinical research patient outcomes expertise and deep understanding of treatment protocols underpin their ability to address evolving evidence requirements.

• Advanced Scientific & Digital Engagement:The Senior GMAL blends scientific expertise with strong digital acumen. They leverage digital health tools advanced analytics and data platforms to transform evidence communication personalize stakeholder engagement and enhance patient outcomes. They are the voice of medicalcrafting compelling narratives driving digital dissemination of evidence and ensuring accurate impactful and compliant scientific communications.

Guiding and Influencing Stakeholders:With significant expertise in internal and external engagement the Senior GMAL builds and sustains powerful relationships across the healthcare ecosystemincluding global and regional KOLs professional societies regulators payers patient organizations digital innovators and health systems. Their credibility and influence enable them to mobilize support for medical strategy evidence generation and healthcare

• change initiatives. They mentor and guide cross-functional teams championing scientific leadership and strategic collaboration.

• Regulatory Insight & Compliance:The Senior GMAL possesses keen regulatory understanding and ensures clinical trial and evidence generation initiatives are designed for both scientific and regulatory success. They anticipate evolving regulatory and payer requirements for evidence ensuring high quality compliant data generation and communication at every stage.

Date Posted

Closing Date

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