Senior Director, Commercial Forecasting & Artificial Intelligence

JoinImmaticsandshape thefuture ofcancerimmunotherapy; one patient at atime!

Immaticsis committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting ofPRAME a target expressed in more than 50 cancers. Ourcutting-edgescience and robust clinical pipeline form the broadestPRAMEfranchise with the mostPRAMEindications and modalities spanning TCR T-cell therapies and TCRbispecifics.

Why Join Us

• Innovative Environment:Helptopioneeradvancementsincancer immunotherapy.
• Collaborative Culture:Be part ofa diverse team dedicated to yourprofessionalgrowth.
• Global Impact:Contribute to therapiesthatmakealastingimpactonpatientsglobally.

Role Overview

We are seeking a Senior Director Commercial Forecasting & AI combined role. Approximately half of the position is owning demand revenue and patient-flow forecasting across Immatics portfolio from early pipeline opportunity assessment through launch readiness and in-line performance. The other half is serving as the Commercial organizations in-house AI expert: identifying building and scaling AI and generative-AI capabilities that make a small commercial team perform like a much larger one. The successful candidate is a recognized forecasting expert in oncology or cell and gene therapy who has already put AI to practical compliant use in a life sciences commercial setting.

Reports to: VP Commercial Analytics & Operations

Location: Remote U.S.

Salary Range: $240000 $280000

Basic Qualifications:

• Bachelors or equivalent years of experience
• 15 years in Life sciences consultancy biotech pharma or related

PreferredQualifications:

• 7 Years of Forecasting Commercial Analytics or market insights
• Demonstrated expertise building patient-based and epidemiology-driven forecast models from the ground up for both pre-launch and in-line assets.
• Deep working knowledge of pharma/biotech data sources and their strengths and limitations e.g. IQVIA Symphony Health Komodo Definitive Healthcare specialty distributor and 867/852 data SEER and other epidemiology sources clinical registries and syndicated market research.
• Demonstrated hands-on experience applying AI and large language models to real commercial problems in a regulated life sciences environment including practical fluency with LLM platforms prompt engineering retrieval-augmented generation and agentic workflows and a clear-eyed view of where AI does and does not work.
• Working understanding of the compliance and privacy constraints on AI in life sciences (PHI/HIPAA GDPR promotional review data licensing terms emerging AI regulation).
• Advanced Excel modeling plus working proficiency in Python SQL and a visualization tool (Power BI/Tableau).
• Experience across the launch lifecycle in oncology cell and gene therapy rare disease or another specialty/limited-distribution setting.
• Proven ability to operate independently in a lean fast-moving environment and to translate complex quantitative and technical work into decision-ready recommendations for senior stakeholders.
• Direct experience forecasting an autologous CAR-T TCR-T or other engineered cell therapy asset including site activation and manufacturing-constrained demand models.
• Track record of standing up a forecasting or commercial AI capability at a pre-commercial or newly commercial company.
• Exposure to global forecasting and to market access/pricing analytics in specialty oncology.

In thisrole youwill:

• Develop Commercial AI roadmap Serve as the Commercial teams resident AI expert across the full commercial organization: partner with Marketing Market Access Medical Affairs and Field Operations to identify prioritize and sequence high-value AI and generative-AI use cases analytics and forecasting market research synthesis competitive intelligence field enablement content development and promotional review preparation account and KOL intelligence payer and policy monitoring and CRM data quality with a clear view of business impact effort and sequencing.
• Build the operating systems Design build and own AI-powered systems that become how Commercial runs day to day not one-off pilots. Re-engineer the analytics workflow end to end so recurring work runs itself: automated ingestion and QC of claims specialty distributor CRM and third-party data; reconciliation and exception flagging; forecast and dashboard refreshes; self-service analytics layers; recurring report and insight generation; and agentic workflows that take manual assembly off the critical path shifting the teams time from producing numbers to interpreting them.
• Build vs. buy and vendors Evaluate AI platforms and vendors run structured pilots against defined success criteria and make defensible build-versus-buy recommendations.

Travel Requirements:

• 10-15%

What do we offer

AtImmatics we believe in investing in our teams healthsafetyand you can expectif youjoinImmatics

Comprehensive Benefits:

• Competitive rates forHealth Dental and Vision Insurance
• 4 weeksofvacationgrantedup front each year and prorated for firstand lastyearofemployment.
• 12 company paid holidays
• 7daysof sick time
• 100%employer-paidlifeinsuranceup toat 1x annual salary up to one hundred thousand dollars
• 100%employer-paidshort-andlong-Termdisabilitycoverage
• 401(k)withimmediateeligibilityandcompany match. The company will match100% of your contributions upto3% of yourbase salaryfor the first two yearsof employment 4% foryears 2-3 of employment and up to5%of your salaryfrom the fourth year onward of continued employment.
• Partiallypaidparentalleavefor eligible employees.
• Additionalvoluntaryemployee-paidbenefitsandservicesincludingaccidenthospitalindemnityandcriticalillnessinsuranceas well asidentitytheftprotectionandpetinsurance.
  
  

Equal Employment Opportunity

We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard torace color religion sex (including pregnancy childbirth or related medical conditions) sexualorientation gender identity or expression national origin ancestry age marital status disability geneticinformation veteran status or any other status protected by applicable law.

Reasonable Accommodations

We are committed to providing reasonable accommodations to individuals with disabilities and to applicants withsincerely heldreligious beliefs practices or observances. If you require assistance or accommodation during the application or interview process please contact us at.

Work Authorization

Applicants mustbe authorized towork in the United States without the need for current or future sponsorship.

Pre-Employment Requirements

Employment is contingent upon successful completion of a background check referencechecksand pre-employment drug screening wherepermittedby applicable law. For certain rolesadditionalscreenings such as a credit check or motor vehicle record review may berequired where job-related and consistent with business necessity.