Senior Associate Scientist Process Development
Job Location:
Pearl River, NY - USA
Yearly Salary:
Posted:
Application Deadline:
Vacancies:
Job Summary
Pfizers purpose is to deliver breakthroughs that change patients lives. Process Development is at the heart of fulfilling this purpose as we translate advanced science into streamlined robust processes that deliver medicines to patients globally.
As a Senior Associate Scientist within the Early Bioprocess Development (EBPD) group in the Vaccines organization you will apply cutting-edge technologies to accelerate the development of high-quality protein subunit vaccines. This role is highly technical and collaborative requiring deep hands-on expertise in molecular biology cell culture and data-driven process optimization.
Your goals will be:
Optimize cell line development workflows to improve subunit protein expression overall productivity process efficiency and biological robustness of the production systems
Execute fermentation to characterize key performance indicators including cell fitness growth recovery protein production yield protein purity etc.
Perform data analysis to identify patterns establishing quantitative correlations between input parameters such as DNA sequences and output values such as protein yield and quality.
Present experimental data and strategic conclusions at cross-functional meetings contributing to team-wide knowledge sharing.
Collaborating with multi-disciplinary teams and working closely with the cell culture purification mRNA production and analytical groups.
Maintain impeccable timely records in Electronic Laboratory Notebooks (ELNs) and author comprehensive technical/production reports.
Draft review and contribute to internal technical reports and external scientific publications.
Contribute to building a culture that embraces excellence urgency partnerships with key stakeholders continuous learning and improvement increasing technical skill base and other cross-functional expertise.
Ensure all tasks and responsibilities are carried out according to scientific ethical and regulatory standards.
B.S. degree with 3 to 5 years of relevant industry or research experience or M.S. in bioengineering biochemistry chemical engineering or related fields with 0 to 3 years of experience
Experience in aseptic cell culture techniques including cell passaging and maintenance transfection monitoring cell morphology and viability.
Experience in using flow cytometry and cell sorting cytometers as well as flow cytometry analysis software such as FlowJo.
Knowledge and hands-on experience in molecular biology techniques including DNA/RNA extraction PCR ddPCR RT-PCR ligation cloning transformation gel electrophoresis SDS-PAGE western blot ELISA.
Well organized self-motivated team-oriented with high attention to detail.
Strong collaborative spirit and communication skills.
Experience in setting up feeding sampling and controlling benchtop or single-use bioreactors (batch fed-batch)
Hands-on knowledge and experience with NGS sequencing platforms.
OTHER JOB DETAILS
Work Location Assignment: On site
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN O-1 H-1B etc.) is not available for this role now or in the future.
Sunshine Act
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race color religion sex sexual orientation age gender identity or gender expression national origin disability or veteran status. Pfizer also complies with all applicable national state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Research and DevelopmentRequired Experience:
Senior IC
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