Scientist IV, Pharmacology Contractor

The Scientist IV Pharmacology Contractor will play a key scientific role in designing executing and interpreting preclinical pharmacology studies to support the discovery and development of novel anti-infective therapeutics. This individual will contribute hands-on scientific expertise across in vitro and in vivo pharmacology pharmacokinetics toxicology PK/PD efficacy studies and data interpretation to support compound advancement from early discovery through preclinical development.

The successful candidate will collaborate closely with cross-functional partners in microbiology medicinal chemistry and clinical development to generate high-quality pharmacology data that informs project strategy and decision-making.

Essential Duties and Responsibilities

• Design develop optimize and execute in vitro ex vivo and in vivo pharmacology studies to evaluate pharmacokinetics efficacy safety and pharmacodynamic response of anti-infective drug candidates.
• Analyze and interpret pharmacology pharmacokinetics toxicology efficacy PK/PD and biomarker data to guide compound selection dose rationale and project progression.
• Contribute to study design for pharmacokinetic toxicology and efficacy models including selection of appropriate models endpoints dosing regimens controls and statistical approaches.
• Prepare study protocols technical reports data summaries presentations and regulatory-supporting documentation as needed.
• Work closely with internal project teams and external CROs to coordinate study execution monitor progress troubleshoot issues and ensure high-quality deliverables.
• Collaborate with microbiology medicinal chemistry and clinical development teams to integrate findings/results into broader drug discovery and development strategies.
• Maintain accurate complete and timely laboratory records and ensure work is conducted in accordance with applicable SOPs safety requirements and scientific best practices.
• Review scientific literature and emerging technologies to identify opportunities to improve pharmacology study design assay performance and translational relevance.
• Present scientific findings and recommendations to project teams leadership and external collaborators as appropriate.
• May mentor junior scientists or research associates providing technical guidance scientific feedback and support for professional development.

Qualifications

• Ph.D. in microbiology pharmacology infectious disease biology pharmaceutical sciences biomedical sciences or a related discipline with 5 years of relevant industry experience; or M.S. with 8 years of relevant industry experience; or B.S. with 10 years of relevant industry experience.
• Strong background in preclinical pharmacology preferably within antibacterial antifungal or mycobacterial drug discovery and development.
• Experience designing and interpreting in vitro and in vivo pharmacology studies including pharmacokinetics toxicology efficacy models PK/PD studies dose-response assessments and biomarker-supported analyses.
• Working knowledge of drug discovery and preclinical development workflows including candidate nomination IND-enabling study support and cross-functional project team interactions.
• Experience coordinating studies with CROs or external collaborators is preferred.
• Strong data analysis scientific writing presentation and communication skills.
• Demonstrated ability to work independently manage multiple priorities troubleshoot scientific challenges and deliver high-quality results in a fast-paced environment.
• Proficiency with commonly used data analysis and visualization tools; experience with pharmacokinetic and PK/PD modeling software is a plus.

On occasion may be asked to work overnight shift or weekend.

Additional Information

The hourly rate for this position is $79 - $102. Individual pay is determined by several factors which include but are not limited to: job-related skills experience and relevant education or training.

DISCLAIMER

The job description is not designed to cover or contain a comprehensive listing of requirements duties or responsibilities that are required of the employee. Other requirements duties and responsibilitiesmay change or be assigned at any time with or without notice.

Shionogi Inc. is an equal opportunity employer supporting individuals with disabilities and veterans. All qualified applicants will receive equal consideration for employment opportunities based on valid job requirements without regard to race color religion sex (including pregnancy) marital status national origin age ancestry citizenship disability genetic information status as a disabled veteran a recently separated veteran Active Duty Wartime or Campaign Badge Veterans and Armed Forces Service Medal Veterans or any other characteristic protected by applicable law. It is the policy of Shionogi Inc. to undertake affirmative action for protected veterans and individuals with disabilities in compliance with all federal state and local requirements to recruit a diverse pool of protected veteran and individuals with disabilities applicants and to ensure that our employment practices are in fact non-discriminatory.

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