Scientist, II

Purpose:

AbbVies CAR-T Biology team in South San Francisco part of the Immuno-Oncology Organization is seeking a Scientist II to support the development of in vivo CAR-T platforms from concept through preclinical development. You will work at the intersection of synthetic biology and immune modulation. The ideal candidate will bring deep expertise in CAR-T biology T-cell functional assays  and therapeutic development. The role includes designing CAR constructs executing advanced cell-based assays and collaborating with cross-functional teams to generate high-quality data that support pipeline programs.

Key Responsibilities:

• Design and execute in vitro assays to evaluate CAR-T biology including assessment of cytotoxicity T-cell effector function and immune cell phenotyping.
• Independently establish track and deliver on project milestones and experimental timelines ensuring alignment with program objectives and organizational priorities while adapting to evolving scientific needs.
• Organize analyze and synthesize complex scientific data and effectively communicate experimental strategies results and interpretations to internal and external stakeholders through clear and impactful presentations and scientific reports.
• Maintain comprehensive and well-documented records in an Electronic Lab Notebook (ELN).

Qualifications :

• BS or equivalent education with typically 7 or more years of experience; or MS or equivalent education with typically 5 or more years of experience in immunology cell and molecular biology or related field.
• Demonstrated ability to independently design perform and interpret key experiments to address scientific questions. Proven capacity to quickly learn and apply new laboratory techniques. Able to manage multiple tasks efficiently while meeting deadlines. Strong skills in scientific writing and verbal communication.
• Previous experience in chimeric antigen receptor (CAR) construct design CAR-T production and T cell function evaluation.
• Deep expertise in primary T cell isolation activation transduction T cell cytotoxicity proliferation cytokine profiling multi-color flow cytometry and immunological assays (e.g. ELISA Luminex cytotoxicity assays) is required.
• Experience in cell-based in vitro assay development and semi-automated liquid handling systems for high-throughput workflows is a plus.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this roleat  the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on manyfactors  including  geographic location and we may ultimately  pay more or less than the posted range. This range may be  modified in the future. 

• We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.

• This job is eligible to  participate in our short-term incentive programs.  

Note: No amount of pay is  considered to be wages or compensation until such amount isearned  vested  and determinable. The amount and availability of  any bonus commission incentive benefits or any other form of compensation and benefits that areallocable to a   particular employee  remains in the Companys sole and absolute discretion unless and until paid and may be  modified at the Companys sole and absolutediscretion  consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more visit  & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:

Work :

No

Employment Type :

Full-time