Scientist II, LNP Platform

We are currently hiring a highly motivated Scientist II to join our LNP Platform this role you will independently execute hands-on formulation and process development activities for emerging tLNP drug product programs with a focus on high-quality execution procedure adherence risk identification and practical problem solving.

This position will report to the Principal Scientist and based at our Worcester office. The role will involve hands-on laboratory work. All duties will be performed in compliance with AbbVies standard operating procedures (SOPs).

Experience in lipid nanoparticle formulation and purification processes or experience with process development engineering and manufacturing of biologics drug product processes is highly desired.

Responsibilities & Duties:

• Execute defined technical projects and experimental plans focused on formulation conjugation purification and process development for targeted lipid nanoparticle-based nucleic acid formulations.
• Prepare formulate purify and characterize nucleic acid-based complex lipid nanoparticle formulations in accordance with established protocols batch records and SOPs.
• Execute and analyze DOE-based and other structured experiments to develop and optimize LNP formulations lyophilized drug products and associated process parameters.
• Identify aberrant results technical issues process variability or formulation performance concerns; support root-cause investigations; raise risks in a timely manner; and propose scientifically sound corrective actions.
• Maintain excellence in laboratory execution including accurate preparation timely completion of tasks clear documentation of experimental procedures and results and compliance with SOPs and other manufacturing-related documentation.
• Prepare high-quality technical reports and presentations that summarize procedures study results data interpretation risks and recommended next steps.
• Collaborate effectively within project and laboratory teams to deliver accurate timely results and support short-term projects with defined technical problems.

Qualifications :

• BS or equivalent education with typically 7 or more years of experience or MS or equivalent education with typically 5 or more years of experience.
• Working knowledge of lipid-based delivery systems formulation science principles nanoparticle characterization and/or drug product process development.
• Hands-on experience working with nucleic acid and/or lipid nanoparticle-based formulations complex/nanoparticle formulations and/or biological formulations development.
• Demonstrated ability to execute laboratory procedures with a high degree of accuracy follow established protocols and SOPs and maintain complete and compliant documentation.
• Ability to recognize technical risks troubleshoot lab or process issues conduct initial root-cause assessments escalate concerns appropriately and propose practical solutions.
• Ability to manage and complete multiple defined tasks or short-term projects under tight timelines while maintaining focus quality and attention to detail.
• Detail oriented with strong organizational skills and a commitment to excellence in execution of laboratory operations.
• Team player with excellent verbal and written communication skills including the ability to clearly communicate progress results risks and recommendations.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this roleat  the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on manyfactors  including  geographic location and we may ultimately  pay more or less than the posted range. This range may be  modified in the future. 

• We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.

• This job is eligible to  participate in our short-term incentive programs.  

Note: No amount of pay is  considered to be wages or compensation until such amount isearned  vested  and determinable. The amount and availability of  any bonus commission incentive benefits or any other form of compensation and benefits that areallocable to a   particular employee  remains in the Companys sole and absolute discretion unless and until paid and may be  modified at the Companys sole and absolutediscretion  consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. 

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Work :

No

Employment Type :

Full-time