Scientist- Cancer immunologyimmunotherapy

We are seeking a motivated and hands-on Scientist- Cancer immunology/immunotherapy with experience in mammalian cell culture and a strong interest in cellular immunology to join our growing research organization. The successful candidate will contribute to the design development and execution of complex immune assays to identify and validate novel targets that support our immuno-oncology research programs. You will work with primary human samples apply key immunological techniques such as flow cytometry and ELISpot and generate high-quality scientific data that will advance our understanding of immune responses and inform the development of innovative therapies.

As a Scientist you will be an integral member of a multidisciplinary team based in Boston collaborating closely with colleagues across discovery and translational research. You will bring strong laboratory skills scientific curiosity and a collaborative mindset to support assay development data generation and scientific decision-making. This role offers the opportunity to contribute directly to novel immunotherapeutic approaches while continuing to develop your expertise in a dynamic and cutting-edge research environment.

Accountabilities

• Design develop and execute complex cellular immunology assays to identify and validate novel targets for cancer immunotherapy research.

• Perform mammalian cell culture including maintenance and manipulation of primary human immune cells such as T cells and other patient-derived cell populations.

• Assess T cell activation functionality and immune responses using techniques including flow cytometry ELISpot and cell-based functional assays.

• Generate analyze interpret and communicate experimental data in a clear and scientifically rigorous manner.

• Maintain detailed and accurate laboratory records in compliance with Good Laboratory Practice (GLP) Safety Health and Environment standards and AstraZeneca policies.

• Collaborate effectively within multidisciplinary teams to share scientific knowledge and support project objectives across research programs.

• Contribute to the optimization and continuous improvement of assay platforms methodologies and laboratory workflows.

• Support the preparation of scientific reports presentations publications and other documentation to communicate research findings.

• Stay current with advancements in immunology and related scientific fields and apply new knowledge to ongoing research activities.

Essential Skills/Experience

• Bachelors degree Masters degree PhD or equivalent experience in Immunology Cell Biology Microbiology Molecular Biology or a related life sciences discipline.

• Hands-on experience with mammalian cell culture including primary human immune cells such as T cells.

• Experience performing immunological assays including flow cytometry (FACS) and ELISpot.

• Working knowledge of biochemical and cellular assay techniques including ELISA and cell-based functional assays.

• Strong analytical skills with the ability to interpret experimental data and draw scientifically sound conclusions.

• Excellent attention to detail and commitment to maintaining accurate laboratory records and documentation.

• Strong organizational communication and collaboration skills with the ability to work effectively in a team environment.

• Demonstrated enthusiasm for scientific learning and a proactive approach to acquiring new skills and knowledge.

Desirable Skills/Experience

• Experience working with patient-derived samples and primary human tissues.

• Knowledge of multi-parameter flow cytometry panel design optimization and analysis using FlowJo or equivalent software.

• Experience with high-content imaging multiplex cytokine analysis or other advanced immunological assay platforms.

• Understanding of antigen-specific T cell biology cancer immunology or vaccine research.

• Experience supporting translational research or biomarker discovery programs.

• Familiarity with experimental design statistical analysis and data visualization tools.

• Previous experience in a pharmaceutical biotechnology or academic research environment.

The annual base pay for this position ranges from $92252.00 - $138378.00. Our positions offer eligibility for various incentivesan opportunity to receive short-term incentive bonuses equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs paid time off (i.e. vacation holiday and leaves) as well as health dental and vision coverage in accordance with the terms of the applicable plans.

Date Posted

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.