Research Senior Scientist

By clicking the Apply button I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takedas Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Pursuant to Section 20 C.F.R. 656.10 you are hereby notified that an application for Alien Employment Certification will be filed by Takeda Development Center Americas Inc. for the following job opportunity:

JOB LOCATION: Cambridge MA

POSITION: Research Senior Scientist

POSITION DESCRIPTION: Takeda Development Center Americas Inc. is seeking a Research Senior Scientist in Cambridge MA with the following duties: serve as the DMPK representative on projects to support gastroenterology autoimmune and oncology Drug Discovery Units (DDUs) for developing novel drug therapy by providing molecular and cellular analysis support; Serve as the DMPK representative on projects to support gastroenterology autoimmune and oncology Drug Discovery Units (DDUs) for developing novel drug therapy by providing molecular and cellular analysis support; support early drug development and translational research by providing scientific support with a focus on cellular and molecular quantification using cutting-edge technology such as flow cytometry ddPCR Nanostring nCounter and other assay platforms; communicate with internal stakeholders regarding the project needs progress updates and DMPK deliverables; perform innovative assay development trouble-shoot bioanalytical assay related issues and actively identify/adopt/develop novel technologies for capability building and to meet the ever-changing needs of projects together with key stakeholders in DMPK different DDUs and other Quantitative Preclinical and Translational Sciences (QPTS) groups; design validate and implement new methodologies and processes (including in silico approaches) that contribute to the research goals of the group/department; summarize and present the experimental results in the cross-functional project teams and DMPK meetings; provide scientific monitoring and guidance to external resources (CRO) for the method transfer development trouble shooting qualification validation and report to support non-/pre-clinical development programs. Ensure the appropriate conduct of studies lead the interpretation of study results and prepare study reports suitable for internal or regulatory use.

The estimated salary range reflects an anticipated range for this position. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/or long-term incentives. U.S. based employees may be eligible to participate in medical dental vision insurance a 401(k) plan and company match short-term and long-term disability coverage basic life insurance a tuition reimbursement program paid volunteer time off company holidays and well-being benefits among others. U.S. based employees are also eligible to receive per calendar year up to 80 hours of sick time and new hires are eligible to accrue up to 120 hours of paid vacation.

REQUIREMENTS: Doctorate degree in Pathobiology or related field. Prior experience must include: lead hypothesis-driven investigative research including in vitro ex vivo and in vivo studies to drive novel therapeutic development including animal handling and biological sample handling; design optimize and implement molecular cellular bioanalytical and biomarker assays including ELISA PCR neutralization assay proliferation flow cytometry and ELISPOT to assess transgenes recombinant proteins cytokines antibodies and immunogenicity for efficacy studies; apply advanced computational and statistical approaches to analyze and interpret large complex datasets to support decisionmaking; analyze nucleotide and peptide sequences using bioinformatics or in silico tools to create and evaluate synthetic primers plasmids and other synthetic genes and peptides to support therapeutics development.

Full time. $137000 - $215270 per year.

Qualified applicants can apply at . Please reference job # R0185712.EOE

Any individual may provide documentary evidence bearing on this application with information on available workers and information on wages and working conditions to the Certifying Officer U.S. Department of Labor Employment and Training Administration Office of Foreign Labor Certification 200 Constitution Avenue NW Room N-5311 Washington DC 20210.