Research Engineer I IIIII (AI Machine Learning)

Who we are

At Gladstone Institutes every role contributes to discoveries that have the potential to transform

lives.

Gladstone is a world-renowned independent nonprofit biomedical research organization dedicated to solving some of the most challenging diseases affecting humanity. Our scientists are leaders in neuroscience cardiovascular disease immunology stem cell biology and emerging areas of biomedical innovation. Located in San Franciscos vibrant Mission Bay research hub Gladstone brings together exceptional researchers clinicians and professionals who share a common goal: improving human health through science.

With approximately 600 employees we offer the agility of an independent institute combined with the impact of a globally recognized research organization. We foster a collaborative inclusive culture where employees are encouraged to grow professionally while contributing to work that truly matters.

About the Role

The Jain Lab develops new approaches to understand how oxygen metabolism and vitamins regulate physiology and disease. We combine CRISPR screens multi-omics imaging computational biology and animal models to answer fundamental biological questions and develop new therapies.

We are seeking a highly motivated AI Research Engineer to help build an AI-native research laboratory. You will develop AI systems that access scientific literature laboratory datasets electronic lab notebooks Slack discussions manuscripts protocols and experimental results in order to generate hypotheses critique ideas design experiments and accelerate discovery.

This is a unique opportunity to work at the intersection of frontier AI and experimental biology helping define how AI transforms biomedical research.

What You Will Do

• Design and build systems for ingesting literature datasets electronic lab notebooks Slack discussions meeting transcripts code repositories protocols etc. into a lab knowledge repository (data layer) optimized for search & retrieval of information by AI agents.

• Develop agentic AI systems that reason across the lab knowledge repository and use external tools to perform multi-step scientific workflows tailored to the labs focus and ways of working.

• Build always-on AI agents that proactively review new papers meetings transcripts etc. and make connections suggest hypotheses & experiments identify flaws or gaps and help with interpretation.

• Collaborate closely with experimental scientists to rapidly prototype and deploy AI tools.

• Evaluate new & emerging AI tools for biomedical research and incorporate state-of-the-art methods into the lab.

What You Will Need

• BS or MS in Computer Science AI Machine Learning Computational Biology Bioengineering or a related quantitative discipline.

• 02 years of research or industry experience (outstanding undergraduate applicants encouraged).

• Strong Python programming skills.

• Strong knowledge of best practices for AI-assisted coding with tools like Claude Code Codex OpenCode etc.

• Strong knowledge of agentic AI fundamentals such as MCP servers/tool calling loops embeddings & vector databases Skills & context engineering and related technologies.

• Experience building projects with LLMs and agentic AI frameworks such a Langchain/Langgraph OpenAI/Gemini/Claude SDK etc.

• Experience with cloud infrastructure (GCP AWS Azure) Docker Git and modern software engineering practices.

• Interest in biology and enthusiasm for learning molecular biology and biomedical research.

• Excellent communication and collaboration skills.

What Is Preferred

• Coursework or research experience in molecular biology genetics computational biology or bioinformatics.

• Experience with biological datasets (RNA-seq CRISPR screens imaging proteomics metabolomics).

• Experience developing AI agents that interact with APIs databases or external tools.

• GitHub open-source contributions or substantial personal AI projects.

Who Should Apply

We are looking for someone who loves building things learns new technologies quickly and is excited about applying frontier AI to scientific discovery. You do not need extensive industry experience but you should have demonstrated initiative through research projects internships open-source contributions or personal projects involving LLMs or agentic AI systems. You will work closely with researchers across Gladstone Arc Institute UCSF and collaborating laboratories.

Salary Range:

$78000-$114000

Gladstone Perks & Benefits

• Peoplework with talented committed and supportive teammates within an organization that values each member of its community.

• A meaningful place to grow and learnwhether its your professional skills or scientific knowledge we have the resources and environment to advance either so you can better support Gladstones mission to drive a new era of discovery in disease-oriented science and to mentor tomorrows leaders in an inspiring and excellent environment.

• Healthy work/life balanceyou are highly engaged and productive at work because you can have time to recharge and enjoy a vibrant life outside of work.

• Compensationcompetitive salary. Title and salary will be commensurate with education and experience.

• Excellent benefitsgenerous medical dental vision retirement plan paid vacation commuter benefits access to free shuttle transportation.
  

Gladstone is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race color sex religion national origin ancestry age marital status medical condition physical or mental disability veteran status sexual orientation or any other non-job related characteristic. We make all employment decisions so as to further this principle of equal employment.