Research Associate IISenior Research Associate, Analytical Development
Job Location:
Cambridge, MA - USA
Monthly Salary:
Posted:
Application Deadline:
Vacancies:
Job Summary
POSITION SUMMARY
We are seeking a highly motivated individual to join the Analytical Development team as a Research Associate II / Senior Research Associate. This position is an excellent opportunity to help develop new gene editing and xenotransplantation products in an exciting and dynamic environment focused on cutting-edge molecular and cellular engineering technology.
In this role you willbe part ofa small team responsible for developing and qualifying methods to assess transgene expression and function in genetically modified porcine cells. This role will involve significant cell culture work including the isolationgrowthand maintenance of primary cells such as endothelial cells from variousporcineorgans and characterizing these cells using techniques such as flow cytometryELISA and be successful in this role you will leverage previous experience with immunological and genomic role is a full-time lab-based position in which being proactive determined responsible coachable and collaborative will help you thrive.
- Independently plandevelopment optimization troubleshooting and executionofrobust and reproducibleanalyticalassaysto characterize geneticallyeditedporcineanimals
- Utilize various techniques to test the primary cells and/or factors they produce through routine analytical testing (including flow cytometry ELISA conventional and real-time PCR etc)
- Proactively monitor track and bridge critical reagent inventory (e.g. cell lines assay standards antibodies) to maintain continuous laboratory workflow without supply gaps or delays
- Independently identify assay anomalies or failures conduct root-cause analyses and propose paths forward to drive group goals to timely completion
- Optimize laboratory time and material resources through disciplined sample batching and full-plate assay executions
- Partner closely with QC to lead and support internal technology transfers of analytical methods ensuring seamless assay transitions robustness and cross-functional alignment
- Communicate and present scientific findings at group and company meetings
- Consistently document experimental procedures and data in ELNs within standard departmental turnaround timelines
- Contribute to multiple research projects as they arise in our fast-paced start-up environment
- Build our laboratory efforts by maintaining and adding to a productive and fun environment
- least4yearsof industry experiencein cell biology immunologybiomedicalengineeringor related discipline
- Prior experience in development troubleshooting and routine execution of assays to characterize and measure transgene expression and potency using a variety of methodologies particularly flow cytometry and ELISA
- Proficiency in growing and maintaining mammalian primary cells/cell lines in culture and aseptic cell culture techniques
- Expertise in general cellular and molecular biology techniques including ELISA flow cytometry (FACS) and potency assays
- Demonstrated ability to self-manage daily schedules independently prioritize tasks across multiple concurrent projects and adapt efficiently in a fast-paced environment
- Proven track record of optimizing lab efficiency including sample batching material resource management and proactive inventory tracking systems.
- Strong interpersonal skills and ability to work in teams
Required Experience:
Senior IC
