Principal Scientist (Antibody Engineering)

GigaGen a subsidiary of Grifols discovers and develops next-generation recombinant antibody therapeutics. Our core technology utilizes a microfluidic droplet system to capture and immortalize diverse immune repertoires which can then be mined for exceptional monoclonals or enriched and used as high-potency polyclonal therapeutics. Our pipeline includes several recombinant polyclonal products for infectious diseases and a monoclonal antibody with a unique mechanism for oncology with several projects in the clinic.

We are seeking an innovative and experienced Principal Scientist to direct protein engineering and molecular biology projects as a part of the Technology Development team. This team initiates and leads early-stage research projects with the goal to improve the platform technology and build a toolbox for our next-generation of recombinant antibody therapeutics. The successful candidate will have significant experience in antibody and antigen engineering protein expression and purification and advanced cloning techniques. Additional expertise in mammalian synthetic biology single-cell assays bioinformatics automation droplet microfluidics bacterial or yeast biology or related areas may also be beneficial. A proven track-record of innovation as evidenced through publications and patents is expected.

Primary responsibilities for role:

• Independently design and manage experiments for testing next-generation antibody therapeutics including construct design expression and purification strategies and implementation of novel analytical assays.
• Provide technical leadership for complex projects which may include elements of protein engineering synthetic biology high-throughput sequencing and in vitro assays.
• Contribute ideas for new assays and technologies to enable the next-generation of GigaGen products and work with management to obtain support and resources to be successful.
• Stay abreast of cutting-edge tools and new technologies related to GigaGens antibody discovery platform and coordinate for testing and implementation
• Contribute to brainstorming sessions and troubleshooting efforts within the team
• Propose and manage goals timelines and personnel for multiple projects and drive internal and external communications within and across teams to ensure goals are met on time
• Synthesize and interpret complex data for internal and external presentations
• Mentor junior lab staff with opportunities for management of one or more staff
• Initiate and manage projects with external vendors

Required experience skills and education qualifications:

• PhD in chemical/biological engineering biochemistry molecular biology or similar preferred
• 8 years industry and/or Post-PhD experience OR MS with 12 years of industry experience OR Bachelors with 15 years of industry experience
• Strong background in a relevant scientific field as evidenced by publications and conference presentations
• Broad technical background covering additional areas of interest
• Experience managing and mentoring direct reports
• Experience managing CROs and external collaborations
• Technical writing skills and experience authoring SOPs manuscripts or other documents
• Ability to work in a fast-paced team environment meet deadlines and prioritize work across multiple projects
• Strong written and verbal communication skills and efficient in communicating in interdisciplinary and cross-functional teams
• Advanced ability to creatively apply scientific principles in problem solving in potentially novel areas.

Occupational Demands:

Work is performed in a clinical and/or a laboratory environment. Exposure to biological fluids with potential exposure to infectious organisms. Exposure to electrical office equipment. Exposure to chemicals. Personal protective equipment required such as protective eyewear garments and gloves. Frequently sits and bends neck for 4-6 hours per day. May stand and twist neck for 2-4 hours per day. Occasionally walks bends and twists waist and squats. Frequent hand movement of both hands with the ability to make fast simple movements of the fingers hands and wrists. Ability to make precise coordinated movements of the fingers to grasp and manipulate objects. Moderate lifting of 15-30lbs. with a maximum lift of 35 lbs. May reach above and below shoulder height. Color perception/discrimination near vision and far vision correctable in one eye to 20/30 and to 20/100 in the other eye. Able to communicate complex information and ideas so others will understand; with the ability to listen to and understand information and ideas presented through spoken words and sentences. Frequently works with diverse groups to obtain consensus on complex issues. Ability to apply abstract principles to solve complex conceptual issues. Performs a wide range of complex tasks as dictated by variable demands and changing conditions with little predictability as to the occurrence.

The estimated pay scale for Principal Scientistrole based inCalifornia is $165000.00 to $205000.00 per year. Additionally the position is eligible to participate inthecompanybonus pool. We offer a wide variety of benefits including but not limited to: Medical Dental Visionlife insurancePTOpaid holidays andup to 5% 401(K) match and tuition reimbursement. Final compensation packages willultimately dependon education experience skillset knowledge where the role is performed internalequityand market data. We are committed to offering our employees opportunities for professional growth and career progression. Grifols is a global healthcare organization with employees in 30 countries focused on patient health and providing impactful results. Since our humble beginnings in 1909 Grifols has been a family company that prides itself on its family-like culture. Our company has more than tripled over the last 10 years and you can grow with us!

Third Party Agency and Recruiter Notice:

Agencies that present a candidate to Grifols must have an active nonexpired Grifols Agency Master Services Agreement with the Grifols Talent Acquisition Department. Additionally agencies may only submit candidates to positions that they have been engaged to work on by a Grifols Recruiter. All resumes must be sent to a Grifols Recruiter under these terms or they will be considered a Grifols candidate.

Grifols provides equal employment opportunities to applicants and employees without regard to race; color; sex; gender identity; sexual orientation; religious practices and observances; national origin; pregnancy childbirth or related medical conditions; status as a protected veteran or spouse/family member of a protected veteran; or disability. We will consider for employment all qualified applicants in a manner consistent with the requirements of all applicable laws including but not limited to the California Fair Chance Act the Los Angeles County Fair Chance Ordinance for Employers and the City of Los Angeles Fair Chance Initiative for Hiring Ordinance.

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Location:NORTH AMERICA : USA : CA-San Carlos:USSCAR2 - San Carlos CA-Shoreway Road-GG

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