Principal Manager, Clinical Operations Lead

JoinImmaticsandshape thefuture ofcancerimmunotherapy; one patient at atime!

Immaticsis committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting ofPRAME a target expressed in more than 50 cancers. Ourcutting-edgescience and robust clinical pipeline form the broadestPRAMEfranchise with the mostPRAMEindications and modalities spanning TCR T-cell therapies and TCRbispecifics.

Why Join Us

• Innovative Environment:Helptopioneeradvancementsincancer immunotherapy.

• Collaborative Culture:Be part ofa diverse team dedicated to yourprofessionalgrowth.

• Global Impact:Contribute to therapiesthatmakealastingimpactonpatientsglobally.

Role Overview

We are seeking a Principal Manager Clinical Operations Lead to support our Clinical Operations team. The Clinical Operations Lead will be responsible for the oversight execution and operational management of US regional clinical trials in support of our clinical development programs.

Reports to: Associate Director Clinical Asset Management

Location: US Fully Remote

Salary Range: $165000 - $180000

Basic Qualifications:

• Bachelors degreein life science nursing or similar

• 7 years of demonstrated leadership of global clinical operations in the pharmaceutical or biotechnology industry including clinical trial oversight vendor management and cross-functional study leadership

Preferred Qualifications:

• Masters Degree preferably in life science nursing or similar

• Noted experience in late phase or launch in oncology.

• Experience cell and/or gene therapy or other complex biologic clinical development programs

• Demonstrated ability to drive process improvements and operational excellence initiatives

• Ability to understand and navigate complex clinical development processes and cross-functional interdependencies and collaborate with stakeholders outside of Clinical Operations

• Strong analytical and problem-solving skills with the ability to assess operational impact across broader cross-functional environments

• Ability to operate effectively in a fast-paced and evolving clinical research environment

In this role you will:

• Lead clinical trial execution and operational delivery across internal and external stakeholdersfrom study start-up through execution

• Provide oversight of CROs vendors and clinical trial partners to ensure quality compliance timelines and budget objectives are achieved

• Serve as the Clinical Operations leader for the team of CTMs CRAs and CTAs for each assigned project

• Drive risk identification issue escalation and mitigation planning across assigned studies

• Support study start up site feasibility enrollment and operational execution activities

• Partner cross-functionally with Clinical Development Regulatory Safety Biometrics Supply Chain Program Leadership and external vendors

• Contribute to SOP development process optimization inspection readiness and operational excellence initiatives

• Mentor and coach junior Clinical Operations team members as applicable

What do we offer

AtImmatics we believe in investing in our teams healthsafetyand you can expectif youjoinImmatics

Comprehensive Benefits:

• Competitive rates forHealth Dental and Vision Insurance

• 4 weeksofvacationgrantedup front each year and prorated for firstand lastyearofemployment.

• 12 company paid holidays

• 7daysof sick time

• 100%employer-paidlifeinsuranceup toat 1x annual salary up to one hundred thousand dollars

• 100%employer-paidshort-andlong-Termdisabilitycoverage

• 401(k)withimmediateeligibilityandcompany match. The company will match100% of your contributions upto3% of yourbase salaryfor the first two yearsof employment 4% foryears 2-3 of employment and up to5%of your salaryfrom the fourth year onward of continued employment.

• Partiallypaidparentalleavefor eligible employees.

• Additionalvoluntaryemployee-paidbenefitsandservicesincludingaccidenthospitalindemnityandcriticalillnessinsuranceas well asidentitytheftprotectionandpetinsurance.

Equal Employment Opportunity

We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard torace color religion sex (including pregnancy childbirth or related medical conditions) sexualorientation gender identity or expression national origin ancestry age marital status disability geneticinformation veteran status or any other status protected by applicable law.

Reasonable Accommodations

We are committed to providing reasonable accommodations to individuals with disabilities and to applicants withsincerely heldreligious beliefs practices or observances. If you require assistance or accommodation during the application or interview process please contact us at.

Work Authorization

Applicants mustbe authorized towork in the United States without the need for current or future sponsorship.

Pre-Employment Requirements

Employment is contingent upon successful completion of a background check referencechecksand pre-employment drug screening wherepermittedby applicable law. For certain rolesadditionalscreenings such as a credit check or motor vehicle record review may berequired where job-related and consistent with business necessity.