Principal Formulations Scientist

Eurofins PSS West is looking for a Principal Formulations Scientist to develop and characterize formulations on complex and poorly behaved drug candidates advance data management and documentation practices and partner in the innovative application of AI at a client site in San Diego CA. This scientist combines hands-on lab skills with data-driven modeling-based assessment of compounds. They are expected to work independently and act as a technical resource for the team.

Responsibilities include but are not limited to:

• Design and develop prototype and complex formulations (solutions suspensions and enabling formulations) for oral subcutaneous and/or intravenous (sterile) delivery to support in-vitro and in-vivo studies.
• Formulate and characterize poorly behaved compounds including those with low solubility or poor stability and develop strategies to overcome their limitations.
• Contribute to compound risk assessments utilizing physicochemical property information in vivo performance data and predictive tools.
• Design and interpret studies of solubility chemical and physical stability and in-vitro performance (non-sink dissolution precipitation).
• Apply analytical techniques (HPLC DSC PXRD spectroscopy) both conceptually and in the lab to characterize compounds and formulations.
• Use physiologically based pharmacokinetic (PBPK) and physiologically based biopharmaceutics modeling (PBBM) tools such as GastroPlus to predict compound and formulation performance.
• Partner in the novel application of AI in the advancement of new molecules.
• Curate data from contract research organizations (CROs) and other external partners.
• Write and review study protocols and technical reports.
• Record work in an ELN and help develop ELN standards and best practices.

Qualifications :

The Ideal Candidate would possess:

• Experience with complex formulations and with formulating and studying poorly behaved compounds
• Experience performing compound risk assessments
• Strong analytical skills both conceptual and hands-on in the lab
• Experience with prompting and the application of AI
• Excellent communication organization and attention to detail
• Experience with GastroPlus or other PBPK/PBBM software
• Experience with statistical analysis
• ELN experience including developing ELN standards

Basic Minimum Qualifications:

• PhD in Pharmaceutical Sciences Chemistry Chemical Engineering or a related field with 02 years of related experience
• Authorization to work in the United States indefinitely without restriction or sponsorship
• Candidates within commuting distance of San Diego CA are encouraged to apply

Additional Information :

• Comprehensive medical coverage with dental and vision options
• Life and disability insurance
• 401(k) with company match
• Paid holidays and vacation

• Compensation Range: $90000-$115000/yr

Eurofins Lancaster Laboratories Professional Scientific Services (PSS) is a global award-winning insourcing solution that places our people at our clients site dedicated to running and managing laboratory services while eliminating headcount co-employment and project-management worries.

We infuse our 55-year track record of scientific and laboratory operations expertise as well as HR and great place to work best practices to recruit hire train and manage highly qualified scientists to perform laboratory services using our clients quality systems and equipment.

We are looking forward to receiving your application including your expected salary and possible start date via our career website.

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

Remote Work :

No

Employment Type :

Full-time