Postdoctoral Scholar, Multigene Expression Platforms

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About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

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We are searching for the best talent for a Postdoctoral Scholar Multigene Expression Platforms to be located in Spring House PA.

Purpose: This postdoctoral position focuses on advancing nextgeneration CHO cell line engineering strategies to enable efficient and stable expression of complex multigene biologics including bispecific and multispecific antibodies. The role will lead the design construction and evaluation of compact multigene expression architectures to address payload size and gene copy number limitations that constrain productivity in current manufacturing platforms. Through a combination of molecular biology cell line development and analytical characterization the position will generate scalable expression solutions that improve integration efficiency transcriptional balance and antibody titers directly supporting portfoliolevel biologics manufacturing innovation within Discovery Product Development & Supply (DPDS).

You will be responsible for:

• Conducting research to advance biologics development platforms through innovative experimental design and data analysis.
  
• Applying molecular and cellbased technologies to evaluate strategies that improve productivity and scalability in cell culture systems.
  
• Collaborating within a multidisciplinary research environment to generate insights that support nextgeneration therapeutic development.
  
• Completing trainings literature reviews presentations and symposia.
  

Qualifications/Requirements

Education:

• A PhD in Molecular Biology Cell Biology Microbiology Biochemistry or a closely related field relevant to biologics or cellular systems is required.
  

Experience and Skills:

Required:

• Advanced knowledge in molecular biology cell biology or a related field with demonstrated expertise in gene expression systems vector design and cellbased biologics research is required.
  
• Advanced experimental design and data analysis skills including the ability to independently plan implement and interpret complex biological data and trouble shoot is required.
  
• Extensive experience with molecular biology mammalian cell culture systems applying advanced laboratory techniques to evaluate expression stability and productivity in engineered cells is required.
  
• Strong proficiency in molecular and analytical methods used to design plasmid constructs for protein expression and to assess genetic integration transcriptional output and protein expression with the ability to critically evaluate data quality and relevance is required.
  
• A strong research record demonstrated through peerreviewed publications and/or scientific presentations is required.
  
• Advanced scientific communication skills including clear documentation data visualization and presentation of findings to multidisciplinary research teams is required.
  
• Ability to work independently as a scientific contributor while effectively collaborating in a teambased research environment and managing multiple priorities is required.
  
• Proficiency with scientific computing data analysis tools standard laboratory software systems and documentation platforms is required.
  

Preferred:

• Experience with advanced or nonconventional gene expression architectures such as multigene and expression systems in mammalian cells is preferred.
  
• Familiarity with platform or technologyfocused research environments where experimental outcomes inform broader design or development strategies beyond a single construct or molecule is preferred.
  
• Exposure to biologics development or translational research settings including collaboration across molecular biology analytics and process oriented teams is preferred.
  

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation external applicants please contact us via internal employees contact AskGS to be directed to your accommodation resource.

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