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Lead Platform Engineer


Job Location:

South San Francisco, CA - USA

Monthly Salary: Not provided by the employer
Posted: 16 August 2026 (30+ days ago)
Application Deadline: 13 November 2026
Vacancies: 1 Vacancy

Job Summary

Job Description:

  • Technical lead for the compute data AI and security infrastructure that runs our sequencing operation.
  • You will own core services that orchestrate lab devices (robots sequencers on-prem Linux servers) and the data ingestion pipeline
  • Build cloud infrastructure and data pipelines to house process and deliver terabytes of sequencing data
  • Design infrastructure to orchestrate millions of bioinformatics tasks (queues workflow orchestration scheduling)
  • Build AI infrastructure and internal tooling to enable agentic systems:
  • Quality Scientist Agents - monitor operations end-to-end surface anomalies and intervene/escalate when quality or reliability issues appear
  • Logistics Agents - coordinate drivers around the world to move packages to labs and carriers
  • Bioinformatics Coding Agents - long-running agents for adaptive analysis of diverse sample types with unknown/shifting data distributions

This opportunity aligns with your focus on backend and infrastructure roles in San Francisco within the AI industry. You will be working with a top 1% hiring manager who maintains a streamlined three-step interview process including a final call with the CEO.

Work experience

  • 6 years of experience in platform/backend/infrastructure engineering
  • Must have impactful experience at a startup while it has scaled (ideally Seed - Series C)
  • Can design build reliable distributed systems (queues orchestration state machines) and ship them to production
  • Led projects and mentored engineers on small teams
  • Former successful founder or founding engineer

Education

  • BS in CS Engineering Math Physics or equivalent technical degree

Hard skills

  • Strong AWS orchestration (ECS Batch StepFunctions) Python backend work (FastAPI/Django)
  • Linux server administration and distributed task queues (Celery/SQS)
  • Experience building LLM/agent systems (tooling evaluation safety/permissions prompt workflow design)

Soft skills

  • Very hungry and wanting to take a step up in their career. Senior/Staff - > Lead engineer

Miscellaneous

  • Up to date with newest AI tooling
  • Genuine curiosity about biotech/science domains

Traits to avoid

  • Too hands off doing IC work less than 70% of the time
  • Working on ML infra or training pipelines